Nsbri explorer

National Space Biomedical Research Institute • October 2005 Space Medicine and Health Care
Identifying Multisystem Effect of
Systems Collaborations
Exercise Training/Nutritional Support
NSBRI is working closely with NASA Johnson Based on data from highly trained athletes and Space Center’s Office of Space Medicine and previous bed-rest simulations, Benjamin D. Levine, Health Care Systems leadership, including Mike M.D., Cardiovascular Alterations Team (University of Duncan, M.D., J. D. Polk, D.O., and Kathy Texas Southwestern Medical Center), is examining Johnson-Throop, Ph.D., to optimize the Institute’s whether an integrative countermeasure will be countermeasure and technology development effective against cardiovascular deconditioning, program for high-priority operational needs of skeletal muscle atrophy and bone demineralization. NASA. Several collaborative projects have The bed-rest study examines the combination of resulted, including one involving the development rowing, strength training and a nutritional supplement of standards for fitness of duty. The project will (potassium-magnesium-citrate) as a single integrated define acceptable limits for human health during countermeasure that can be applied in a practical space flight through a series of seven discipline fashion aboard the International Space Station or during lunar exploration-class missions.♦ Another space medicine project addresses risk model development for human exploration medical NSBRI/NASA ConnectTM Program on
capabilities. The medical database and bioinformatics activity will result in development of Sleep and Circadian Rhythm
an accurate model to determine human risk as it NSBRI’s third educational television collaboration pertains to bone, muscle and exercise parameters with NASA ConnectTM aired on September 22. Charles and a risk model to advance technology for Czeisler, Ph.D., M.D., Human Performance Factors, Sleep and Chronobiolgy Team Leader (Harvard Medical School), served as the content expert for The NSBRI Science/Technology Portfolio
Right Ratio of Rest script and appeared in the Partners with Industry
program. The segment also featured activities based on More than 30 companies are affiliated with projects NSBRI’s Sleep and Daily Rhythms teacher activity in NSBRI’s science and technology portfolio. These guide produced by Baylor College of Medicine’s companies represent several industry sectors – NSBRI Education and Outreach Team members. biomedical devices, pharmaceuticals, engineering, NASA ConnectTM, a series of free, integrated math, technology and human performance. Industry partner science, and technology programs for grades 6-8, airs participation varies by project but ranges from supply on PBS and NASA TV and is available on DVD and of material, labor, technology, design, information or As new members are added to the Institute’s Kovacs to Lead External Advisory
Industry Forum, member companies will reflect the depth and breadth of the academic/industry collaborations already active in the NSBRI program. Gregory T. Kovacs, M.D., Ph.D., (Stanford University These industry collaborations enhance NSBRI’s School of Medicine) has been selected as Chairman countermeasure development for space exploration of the Institute’s External Advisory Council. The and serve to expedite Earth spin-offs and commercial Council provides advice to Institute management effectiveness. Kovacs replaces Lawrence A. Palinkas, PhD., (University of Southern California) who is stepping down after five years of excellent service.♦ Meeting Addresses Individual
Moreno, N. P., J. K. Roberts, B. Z. Tharp, J. P. Denk, Differences in Space Flight
P. H. Cutler, and W. A. Thomson. Increasing student learning through space life sciences education. Acta A bioastronautics meeting entitled “Tailoring Astronaut 56(9-12):783-91, 2005. (Education and Countermeasures to Individual Astronaut Needs: Dealing with Individual Variability and Differential Vulnerability to Health and Behavior Risks in Peterson, N. C., M. D. Servinsky, A. Christian, Z. Prolonged Space Flight” took place on October 11 at Peng, W. Qiu, J. Mann, J. Dicello, and D. L. Huso. the University of Pennsylvania School of Medicine in Tamoxifen resistance and Her2/neu expression in an Philadelphia. Sponsored by NSBRI, the meeting aged, irradiated rat breast carcinoma model. brought together representatives from all NSBRI Carcinogenesis 26(9):1542-52, 2005. (Radiation science and technology teams, NASA Headquarters and various NASA Centers, as well as biostatisticians from NASA Johnson Space Center, Massachusetts Xia, Y., W. Lin, and Y-X. Qin. The influence of cortical Institute of Technology and the University of end-plate on broadband ultrasound attenuation Pennsylvania. David F. Dinges, Ph.D., Neuro- measurements at the human calcaneus using behavioral and Psychosocial Factors Team Leader scanning confocal ultrasound. J Acoust Soc Am, (University of Pennsylvania School of Medicine), 118(3), Part 1:1801-1807, 2005. (Technology The conference examined the need to focus on the range of individual responses to space flight risks and Zeitzer, J. M., S. B. Khalsa, D, B. Boivin, J. F. Duffy, T. responses to the countermeasures for differential L. Shanahan, R. E. Kronauer, and C. A. Czeisler. vulnerability to space flight risks. The meeting Temporal dynamics of late night photic stimulation of objective was to ensure that countermeasure the human circadian timing system. Am J Physiol development can effectively progress to meet the Regul Integr Comp Physiol 289(3):R839-R844, 2005. needs of every astronaut, not simply the “average” (Human Performance Factors, Sleep and Chronobiology Recent Publications
Zwart, S. R., J. E. Davis-Street, D. Paddon-Jones, A. A. Ferrando, R. R. Wolfe, and S. M. Smith. Amino Bailey, M. R., Y. A. Pishchalnikov, O. A. Sapozhnikov, acid supplementation alters bone metabolism during R. O. Cleveland, J. A. McAteer, N. A. Miller, I. V. simulated weightlessness. J Appl Physiol 99(1):134- Pishchalnikova, B. A. Connors, L. A. Crum, and A. P. 40, 2005. (Nutrition, Physical Fitness and Evan. Cavitation detection during shock-wave lithotripsy. Ultrasound Med Biol 31(9):1245-56, 2005. Calendar Update
Fiedler, E. R. Operational processes and cognitive mapping. Aviat Space Environ Med 76(7 Suppl):C4-6, NSBRI Board of Directors Telecon
November 9, 2 p.m. Central
2005. (NSBRI/NASA Behavioral Health Liaison)♦ Lafon, C., V. Zderic, M. L. Noble, J. C. Yuen, P. J. Vitamin D and Bone Health: An Update from Earth
Kaczkowski, O. A. Sapozhnikov, F. Chavrier, L. A. and Outer Space
Crum, and S. Vaezy. Gel phantom for use in high- November 15, 9 a.m. – Noon Eastern Jack Morton Auditorium, George Washington intensity focused ultrasound dosimetry. Ultrasound Med Biol, 31(10):1383-89, 2005. (Smart Medical Systems Team and Postdoctoral Fellow)♦ NSBRI Investigator Retreat
Li, C. Y., R. J. Majeska, D. M. Laudier, R. Mann, and M. B. Schaffler. High-dose risedronate treatment partially preserves cancellous bone mass and microarchitecture during long-term disuse. Bone Contact: Kathy Major •

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