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Introduction
PO Box 327
Sandringham House
Harlow Business Park
Harlow
Essex CM19 5TG

01279 775858
01279 775888
ukenquiry@merial.com
www.merial.com
Presentation
Round, yellow tablets each containing 20 mg or 100 mg doxycycline, as doxycycline hyclate.
Uses
For the treatment of respiratory tract infections in cats and dogs, including rhinitis, tonsillitis, bronchopneumonia and feline
respiratory disease. The therapeutic spectrum includes Pasteurella spp., Bordetella bronchiseptica, Staphylococcus aureus, other Staphylococcus spp., and Streptococcus spp.
Dosage and administration
The tablets are for oral administration. The dosage is 10 mg per kg bodyweight (one 20 mg tablet per 2 kg or one 100 mg
tablet per 10 kg) administered daily for up to five days.
Tablets should be administered at feeding times.
Contra-indications, warnings, etc
For animal treatment only.
Do not exceed the recommended dosage.
RONAXAN should not be used in pregnant animals.
Do not use in known cases of hypersensitivity to the active ingredient.
Vomiting, oesophagitis and oesophageal ulcerations have been reported as side effects following doxycycline therapy and
RONAXAN should not therefore be administered to patients with dysphagia, or diseases accompanied by vomiting.
Photodermatitis has occurred following tetracycline therapy after exposure to intense sun or ultraviolet light.
The uses of tetracycline during tooth development may lead to tooth discoloration. Doxycycline, because of the lower affinity for calcium carries a lower risk than other tetracyclines.
Cross resistance to other tetracyclines can occur.
Doxycycline should not be used concurrently with other antibiotics especially bactericidal drugs such as the β-lactams.
Wash hands thoroughly after use.
Handle the tablets with care if you know you are hypersensitive (allergic) to tetracycline. In case of accidental ingestion, Container disposalAny unused product or waste material should be disposed of in accordance with national requirements.
Pharmaceutical precautions
Do not store above 25°C.
Store in a dry place.
Protect from light.
Legal category
Packaging Quantities
Packs of 5 blister strips each containing 10 tablets.
Further information
Cross resistance to other tetracyclines can occur.
Doxycycline should not be used concurrently with other antibiotics especially bactericidal drugs such as the β-lactams.
The half-life of doxycycline is reduced by concurrent administration of barbiturates or phenytoin.
Simultaneous administration of oral absorbants, iron preparations and antacids should be avoided as they reduce
doxycycline availability.
Overdose: the toxicity and tolerance studies have shown that this product is very well tolerated in cats after five times the recommended dose. Raised levels of SGPT, GGT, SAP and total bilirubin were noted in dogs which received three or five times the recommended dose. Some vomiting can occur in dogs with five times the recommended dosage.
Marketing authorisation number
.
Vm 08327/4069: 20mg tablets.
Vm 08327/4068:100 mg tablets.

Source: http://www.vetgb.com/vetgb_pdfs/ronaxan_9328_vetgb.pdf

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