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protocols open at clifton springs hospital and clinic

January 2008
PROTOCOLS OPEN AT
FINGER LAKES HEMATOLOGY AND ONCOLOGY
BREAST:
ECOG-PACCT-1: Program for the Assessment of Clinical Cancer tests (PACCT-1):
Trial assigning individualized options for treatment: The TAILORx Trial (*ER and/or PR +; 1.1 to 5.0 cm tumor; unfavorable features=intermediate or poor nuclear and/or histologic grade, or lymphovascular A Double-Blind Phase III Trial of Doxorubicin and Cyclophosphamide followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer. A Randomized phase III trial of Exemestane vs. Anastrozole in
post menopausal women with receptor positive primary breast
cancer. ****must be eligible for all three studies****
MA.27B(CTSU) The influence of five years of adjuvant Anastrozole or Exemestane on bone mineral density in postmenopausal women
with primary breast cancer. (A companion study to
MA.27)****only osteo arm is open****
MA.27D(CTSU) The association of Breast Density changes, plasma hormone changes, and breast cancer recurrence. (A companion study to MA.27) NSABP B.36 (CTSU) A clinical trial of adjuvant therapy comparing six cycles of 5- fluorouracil, Epirubicin, and Cyclophosphamide (FEC) to four cycle of Adriamycin and Cyclophosphamide (AC) in patients with node-negative breast cancer. Phase III trial of continuous schedule of AC + G vs. Q2 week schedule AC, followed by Paclitaxel given either every 2 weeks or weekly for 12 weeks as post-operative adjuvant therapy in node-positive or high-risk node negative breast cancer. (*stage I-III; tumor > 2 cm and/or one or more axillary nodes +) January 2008
PROTOCOLS OPEN AT
FINGER LAKES HEMATOLOGY AND ONCOLOGY
Phase III randomized trial of Anastrozole vs. Anastrozole and Fulvestrant as first line therapy for post menopausal women with metastatic breast cancer. Phase III Trial of LHRH Analog Administration during Chemotherapy to Reduce Ovarian Failure Following Standard Adjuvant Chemotherapy in Early Stage, Hormone-Receptor Negative Breast Cancer. Cyclophosphamide followed by Paclitaxel with Bevacizumab or Placebo in Patients with Lymph Node Positive and High Risk Lymph Node Negative Breast Cancer. A double blind re-randomization to Letrozole or placebo for women completing five years of adjuvant Letrozole in the MA.17 study.
GASTROINTESTINAL:
A4061020:
A Randomized Phase II study of the Anti-Angiogenesis Agent (AG-013736) in combination with chemotherapy and Bevacizumab in patients with metastatic colorectal cancer preceded by a phase 1 portion. (A Pfizer sponsor study)
GENITOURINARY:
S0421
A Phase III study of Docetaxel and Atrasentan vs. Docetaxel and placebo for patients with Advanced Hormone Refractory Prostate Cancer. LUNG:
E1505 (CTSU)
A Phase III Randomized Trial of Adjuvant Chemotherapy With or Without Bevacizumab for Patients With completely Resected IB (> 4 cm) –IIIA Non-Small Cell Lung Cancer (NSCLC) January 2008
PROTOCOLS OPEN AT
FINGER LAKES HEMATOLOGY AND ONCOLOGY

LYMPHOMA:
E4402 (CTSU)
Randomized phase III trial comparing two different rituximab dosing regimens for patients with low tumor burden indolent Non-Hodgkin’s lymphoma
LAB STUDIES:
S9925
Consent form for use of specimens for research.

Source: http://www.flhocancercare.com/pdfs/clinical-trials.pdf

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