3-IN-ONE PROFESSIONAL AIR DUSTER Chemwatch Independent Material Safety Data Sheet Issue Date: 4-Nov-2010 CHEMWATCH 24-8854 Version No:3 CD 2010/3 Page 1 of 6 Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME 3-IN-ONE PROFESSIONAL AIR DUSTER PROPER SHIPPING NAME 1,1-DIFLUOROETHANE (REFRIGERANT GAS R 152a) PRODUCT USE ■ The use of a quantity of material in an unventilated or confined space may result in increased exposure and an irritating atmosphere developing. Before starting consider control of exposure by mechanical ventilation. Used according to manufacturer's directions. SUPPLIER Company: Pax Australia Pty Ltd Address: PO Box 189 Ingleburn NSW, 1890 Australia Telephone: +61 2 9829 2322 Emergency Tel: 1800 024 973 Fax: +61 2 9829 4815 Section 2 - HAZARDS IDENTIFICATION STATEMENT OF HAZARDOUS NATURE HAZARDOUS SUBSTANCE. DANGEROUS GOODS. According to NOHSC Criteria, and ADG Code.
• Keep away from sources of ignition. No smoking.
metallic compounds. ■ Extremely flammable.
• Do not breathe gas/fumes/vapour/spray.
• Wear suitable protective clothing.
• Use only in well ventilated areas.
• Keep container in a well ventilated place. • To clean the floor and all objects contaminated by thismaterial, use water and detergent. • Keep container tightly closed. • Keep away from food, drink and animal feeding stuffs. • If swallowed, IMMEDIATELY contact Doctor or PoisonsInformation Centre. (show this container or label). • This material and its container must be disposed of ashazardous waste. Section 3 - COMPOSITION / INFORMATION ON INGREDIENTS Section 4 - FIRST AID MEASURES SWALLOWED • Not considered a normal route of entry. • For advice, contact a Poisons Information Centre or a doctor. • Avoid giving milk or oils. • Avoid giving alcohol. EYE • If product comes in contact with eyes remove the patient from gas source or contaminated area. • Take the patient to the nearest eye wash, shower or other source of clean water. • Open the eyelid(s) wide to allow the material to evaporate. • Gently rinse the affected eye(s) with clean, cool water for at least 15 minutes. Have the patient lie or sit down and tilt the head back. Hold the eyelid(s) open and pour water slowly over the eyeball(s) at the inner corners, letting the water run out of the outer corners. continued. 3-IN-ONE PROFESSIONAL AIR DUSTER Chemwatch Independent Material Safety Data Sheet Issue Date: 4-Nov-2010 CHEMWATCH 24-8854 Version No:3 CD 2010/3 Page 2 of 6 Section 4 - FIRST AID MEASURES SKIN ■ If skin contact occurs: • Immediately remove all contaminated clothing, including footwear. • Flush skin and hair with running water (and soap if available). • Seek medical attention in event of irritation. INHALED • Following exposure to gas, remove the patient from the gas source or contaminated area. • NOTE: Personal Protective Equipment (PPE), including positive pressure self-contained breathing apparatus may be required to assure the safety of the rescuer. • Prostheses such as false teeth, which may block the airway, should be removed, where possible, prior to initiating first aid procedures. • If the patient is not breathing spontaneously, administer rescue breathing. NOTES TO PHYSICIAN ■ for intoxication due to Freons/ Halons;
• Maintain an open airway and assist ventilation if necessary• Treat coma and arrhythmias if they occur. Avoid (adrenaline) epinephrine or other sympathomimetic amines that may precipitate ventricular
arrhythmias. Tachyarrhythmias caused by increased myocardial sensitisation may be treated with propranolol, 1-2 mg IV or esmolol 25-100microgm/kg/min IV.
• Monitor the ECG for 4-6 hoursB: Specific drugs and antidotes:• There is no specific antidote. for gas exposures:--------------------------------------------------------------BASIC TREATMENT--------------------------------------------------------------• Establish a patent airway with suction where necessary. • Watch for signs of respiratory insufficiency and assist ventilation as necessary. • Administer oxygen by non-rebreather mask at 10 to 15 l/min. • Monitor and treat, where necessary, for pulmonary oedema . Section 5 - FIRE FIGHTING MEASURES EXTINGUISHING MEDIA ■ DO NOT EXTINGUISH BURNING GAS UNLESS LEAK CAN BE STOPPED SAFELY: OTHERWISE: LEAVE GAS TO BURN. FOR SMALL FIRE: • Dry chemical, CO2 or water spray to extinguish gas (only if absolutely necessary and safe to do so). • DO NOT use water jets. FOR LARGE FIRE: • Cool cylinder by direct flooding quantities of water onto upper surface until well after fire is out. • DO NOT direct water at source of leak or venting safety devices as icing may occur. FIRE FIGHTING ■ -------------------------------------------------------------- GENERAL -------------------------------------------------------------- • Alert Fire Brigade and tell them location and nature of hazard. • May be violently or explosively reactive. • Wear breathing apparatus plus protective gloves. • Consider evacuation. When any large container (including road and rail tankers) is involved in a fire, consider evacuation by 1500 metres in all directions. FIRE/EXPLOSION HAZARD • HIGHLY FLAMMABLE: will be easily ignited by heat, sparks or flames. • Will form explosive mixtures with air • Fire exposed containers may vent contents through pressure relief valves thereby increasing fire intensity and/ or vapour concentration. • Vapours may travel to source of ignition and flash back. Combustion products include: carbon monoxide (CO), carbon dioxide (CO2), hydrogen fluoride, other pyrolysis products typical of burning organic material. Contains low boiling substance: Closed containers may rupture due to pressure buildup under fire conditions. • Vented gas is more dense than air and may collect in pits, basements. FIRE INCOMPATIBILITY • Avoid contamination with oxidising agents i.e. nitrates, oxidising acids, chlorine bleaches, pool chlorine etc. as ignition may result. HAZCHEM 2YE Personal Protective Equipment Breathing apparatus. Gas tight chemical resistant suit. Limit exposure duration to 1 BA set 30 mins. continued. 3-IN-ONE PROFESSIONAL AIR DUSTER Chemwatch Independent Material Safety Data Sheet Issue Date: 4-Nov-2010 CHEMWATCH 24-8854 Version No:3 CD 2010/3 Page 3 of 6 Section 6 - ACCIDENTAL RELEASE MEASURES MINOR SPILLS • Avoid breathing vapour and any contact with liquid or gas. Protective equipment including respirator should be used. • DO NOT enter confined spaces where gas may have accumulated. • Shut off all sources of possible ignition and increase ventilation. • Clear area of personnel. MAJOR SPILLS • Clear area of all unprotected personnel and move upwind. • Alert Emergency Authority and advise them of the location and nature of hazard. • May be violently or explosively reactive. • Wear full body clothing with breathing apparatus. Personal Protective Equipment advice is contained in Section 8 of the MSDS. Section 7 - HANDLING AND STORAGE PROCEDURE FOR HANDLING • Consider use in closed pressurised systems, fitted with temperature, pressure and safety relief valves which are vented for safe dispersal. • Consider the use of doubly-contained piping; diaphragm or bellows sealed, soft seat valves; backflow prevention devices; flash arrestors; and flow monitoring or limiting devices. Gas cabinets, with appropriate exhaust treatment, are recommended, as is automatic monitoring of the secondary enclosures and work areas for release. • Use a pressure reducing regulator when connecting cylinder to lower pressure (<100 psig) piping or systems • Use a check valve or trap in the discharge line to prevent hazardous back-flow into the cylinder. • Avoid generation of static electricity. Earth all lines and equipment. • DO NOT transfer gas from one cylinder to another. SUITABLE CONTAINER • DO NOT use aluminium or galvanised containers. • Cylinder: • Ensure the use of equipment rated for cylinder pressure. • Ensure the use of compatible materials of construction. • Valve protection cap to be in place until cylinder is secured, connected. STORAGE INCOMPATIBILITY ■ 1,1-Difluorethane: • reacts violently with strong oxidisers, barium, sodium and potassium • is incompatible with powdered aluminium, liquid oxygen • may form explosive compounds with divalent light metals and metallic azides • attacks some metals in the presence of moisture. As a general rule, hydrofluorocarbons tend to be flammable unless they contain more fluorine atoms than hydrogen atoms. Haloalkanes: • are highly reactive:some of the more lightly substituted lower members are highly flammable; the more highly substituted may be used as fire suppressants, not always with the anticipated results. • may react with the lighter divalent metals to produce more reactive compounds analogous to Grignard reagents. • may produce explosive compounds following prolonged contact with metallic or other azides • may react on contact with potassium or its alloys - although apparently stable on contact with a wide rage of halocarbons, reaction products may be shock-sensitive and may explode with great violence on light impact; severity generally increases with the degree of halocarbon substitution and potassium-sodium alloys give extremely sensitive mixtures . • Compressed gases may contain a large amount of kinetic energy over and above that potentially available from the energy of reaction produced by the gas in chemical reaction with other substances. STORAGE REQUIREMENTS • Cylinders should be stored in a purpose-built compound with good ventilation, preferably in the open. • Such compounds should be sited and built in accordance with statutory requirements. • The storage compound should be kept clear and access restricted to authorised personnel only. • Cylinders stored in the open should be protected against rust and extremes of weather. Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION EXPOSURE CONTROLS The following materials had no OELs on our records • 1, 1- difluoroethane: PERSONAL PROTECTION RESPIRATOR Type AX Filter of sufficient capacity continued. 3-IN-ONE PROFESSIONAL AIR DUSTER Chemwatch Independent Material Safety Data Sheet Issue Date: 4-Nov-2010 CHEMWATCH 24-8854 Version No:3 CD 2010/3 Page 4 of 6 Section 8 - EXPOSURE CONTROLS / PERSONAL PROTECTION EYE • Safety glasses with side shields. • Chemical goggles. • Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. A written policy document, describing the
wearing of lens or restrictions on use, should be created for each workplace or task. This should include a review of lens absorption andadsorption for the class of chemicals in use and an account of injury experience. Medical and first-aid personnel should be trained in theirremoval and suitable equipment should be readily available. In the event of chemical exposure, begin eye irrigation immediately and remove contactlens as soon as practicable. Lens should be removed at the first signs of eye redness or irritation - lens should be removed in a clean environmentonly after workers have washed hands thoroughly. [CDC NIOSH Current Intelligence Bulletin 59]. HANDS/FEET • When handling sealed and suitably insulated cylinders wear cloth or leather gloves. OTHER • The clothing worn by process operators insulated from earth may develop static charges far higher (up to 100 times) than the minimum ignition
energies for various flammable gas-air mixtures. This holds true for a wide range of clothing materials including cotton.
• Avoid dangerous levels of charge by ensuring a low resistivity of the surface material worn outermost. BRETHERICK: Handbook of Reactive Chemical Hazards. • Protective overalls, closely fitted at neck and wrist. • Eye-wash unit. IN CONFINED SPACES:• Non-sparking protective boots• Static-free clothing. • Some plastic personal protective equipment (PPE) (e.g. gloves, aprons, overshoes) are not recommended as they may produce static electricity. • For large scale or continuous use wear tight-weave non-static clothing (no metallic fasteners, cuffs or pockets), non sparking safety footwear. ENGINEERING CONTROLS • Areas where cylinders are stored require good ventilation and, if enclosed need discrete/ controlled exhaust ventilation. • Vented gas is flammable, may be denser than air and will spread. Vent path must not contain ignition sources, pilot lights, naked flames. • Secondary containment and exhaust gas treatment may be required by certain jurisdictions. • Local exhaust ventilation (explosion proof) is usually required in workplaces. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES APPEARANCE Clear colourless compressed gas with a slight ethereal odour; partly mixes with water. PHYSICAL PROPERTIES Gas. Section 10 - STABILITY AND REACTIVITY CONDITIONS CONTRIBUTING TO INSTABILITY • Presence of incompatible materials. • Product is considered stable. • Hazardous polymerisation will not occur. For incompatible materials - refer to Section 7 - Handling and Storage. Section 11 - TOXICOLOGICAL INFORMATION POTENTIAL HEALTH EFFECTS ACUTE HEALTH EFFECTS
■ Vapours may cause dizziness or suffocation. TOXICITY AND IRRITATION 3-IN-ONE PROFESSIONAL AIR DUSTER: ■ Not available. Refer to individual constituents.
1,1-DIFLUOROETHANE:■ unless otherwise specified data extracted from RTECS - Register of Toxic Effects of Chemical Substances. continued. 3-IN-ONE PROFESSIONAL AIR DUSTER Chemwatch Independent Material Safety Data Sheet Issue Date: 4-Nov-2010 CHEMWATCH 24-8854 Version No:3 CD 2010/3 Page 5 of 6 Section 11 - TOXICOLOGICAL INFORMATION
Oral (rat) LD50: 484 mg/kgOral (Rat) LD: >1500 mg/kgInhalation (Rat) LC: 64000 ppm/4hInhalation (Mouse) LC50: 977000 mg/m³/2h■ For 1,1-difluoroethane:1,1 -Difluoroethane is practically non-toxic following acute or chronic inhalation exposures. It is not a developmental or reproductive toxicant inrat studies and is negative for cancer in a two year rat inhalation study. Section 12 - ECOLOGICAL INFORMATION
This material and its container must be disposed of as hazardous waste. Ecotoxicity Ingredient Section 13 - DISPOSAL CONSIDERATIONS
• Evaporate or incinerate residue at an approved site. • Return empty containers to supplier. • Ensure damaged or non-returnable cylinders are gas-free before disposal. Section 14 - TRANSPORTATION INFORMATION F L A M M A B L E HAZCHEM: 2YE (ADG7) ADG7: Class or division:
Special packingprovisions:Name and description: 1,1-DIFLUOROETHANE (REFRIGERANT GAS R 152a)
Land Transport UNDG: Class or division:
Shipping Name:1,1-DIFLUOROETHANE (REFRIGERANT GAS R 152a)
Air Transport IATA: ICAO/IATA Class: continued. 3-IN-ONE PROFESSIONAL AIR DUSTER Chemwatch Independent Material Safety Data Sheet Issue Date: 4-Nov-2010 CHEMWATCH 24-8854 Version No:3 CD 2010/3 Page 6 of 6 Section 14 - TRANSPORTATION INFORMATION Maritime Transport IMDG: IMDG Class:
Shipping Name: 1,1-DIFLUOROETHANE (REFRIGERANT GAS R 152a)
Section 15 - REGULATORY INFORMATION REGULATIONS Regulations for ingredients 1,1-difluoroethane (CAS: 75-37-6) is found on the following regulatory lists; "Australia Inventory of Chemical Substances (AICS)","International Council of Chemical Associations (ICCA) - High Production Volume List","OECD Representative List of High Production Volume (HPV) Chemicals" No data for 3-IN-ONE Professional Air Duster (CW: 24-8854) Section 16 - OTHER INFORMATION
■ Classification of the preparation and its individual components has drawn on official and authoritative sources as well as independent review by the Chemwatch Classification committee using available literature references. A list of reference resources used to assist the committee may be found at: www.chemwatch.net/references.
■ The (M)SDS is a Hazard Communication tool and should be used to assist in the Risk Assessment. Many factors determine whether the reported Hazards are Risks in the workplace or other settings. This document is copyright. Apart from any fair dealing for the purposes of private study, research, review orcriticism, as permitted under the Copyright Act, no part may be reproduced by any process without writtenpermission from CHEMWATCH. TEL (+61 3) 9572 4700.
Issue Date: 4-Nov-2010Print Date: 8-Nov-2010
Jordan F. Karp, MD Bruce Rollman, MD, MPH Debra Weiner, MD Jill A. Tarr, LCSW Principal Investigator Co-Investigator Co-Investigator Project Coordinator ADAPT: ADDRESSING DEPRESSION AND PAIN TOGETHER 2011 Summer What is ADAPT? Funded by the National Institute on Aging for the next 4 years, the ADAPT study will test whether combined treatment with antidepressant medication
CORRECTION EXERCICE CALCULS DE DOSES n° 7 EXERCICE 1 Monsieur Ignace présente une maladie de Hodgkin de type scléro-nodulaire de stade IV. Il est hospitalisé pour une cure de chimiothérapie le 19/11 à 16 h 30. - Kytril® IV (anti-émétique), 1 ampoule de 3 mL dosée à 3 mg dans une poche de 50mL de NaCl 0,9 % sur 15 mn, une _ heure avant le début des antinéoplasiques,- Holoxan®