Publikationsliste tobiassaam

PUBLIKATIONSLISTE

Priv.-Doz. Dr. med. Tobias Saam
Institut für Klinische Radiologie
Marchioninistr. 15
81377 München
ZUSAMMENFASSUNG

17 Erst-Autorschaften, davon 13 Originalarbeiten, 3 Übersichtsartikel und 1 Fal bericht mit
einem kumulierten Impact Faktor von 66,8
3 Letzt-Autorschaften, davon 2 Übersichtsartikel und eine Clinical Note mit einem Impact
Faktor von 8,4
18 Co-Autorschaften, davon 16 Originalarbeiten, 1 Übersichtsartikel und 1 Fal bericht mit
einem kumulierten Impact Faktor von 81,9
Anzahl der Zitierungen laut Google Scholar > 1000
> 25 Vorträge auf Wissenschaftlichen Kongressen
> 30 Wissenschaftliche Poster
PREISE UND AUSZEICHNUNGEN
1. Platz Coolidge Award (Innovationspreis für die Bildgebende Radiologische Diagnostik
von General Electric) für die Habilitationsschrift „Methodische Entwicklung und klinische
Evaluierung der hochaufgelösten Magnetresonanztomographie atherosklerotischer Plaques
in den Karotiden“
Young Investigator Award beim 3. Internationalen Symposium “Integrated Biomarkers in
Cardiovascular Diseases”, Seattle, WA, USA, 2008 für den Abstract “Increased Arterial Wal
18F-FDG-Uptake Identifies Patients at Risk for Future Cardiovascular Events: A PET-CT
Study Considering Age and Cardiovascular Risk Factors”
1. Preis “Best Scientific Paper Awards 2007” im Themengebiet "Vascular" beim
Europäischen Röntgenkongress in Wien, 2007 für den Abstract “Prevalence of AHA Type
VI Carotid Atherosclerotic Lesions Identified by MRI for Different Levels of Stenosis as
Measured by Duplex Ultrasound”
Novartis Stipendium für Therapeutische Forschung 2007 für das Projekt „Darstel ung
der Plaquemorphologie der Karotiden durch Dual-Source CT und 3.0T MRT: Validierung im
Vergleich zur Histopathologie sowie Korrelation der Plaquemorphologie mit klinischen
Parametern“
3. Platz „Berlex Best Poster Awards” sowie “Travel Grant” bei der 32. Jahrestagung der
North American Society for Cardiac Imaging, Amelia Island, Florida, USA, 2004 für den
Abstract “Quantitative and Morphological Assessment of Carotid Atherosclerotic Plaque
Symmetry Using Noninvasive Magnetic Resonance Imaging”
Educational Grant für Nachwuchswissenschaftler 2003 beim XIII. Internationalen
Atherosklerose Symposium, Kyoto, Japan für den Abstract “Differences in Carotid Artery
Atherosclerotic Lesion Characteristics from the Index- and Non-index Side of Symptomatic
Patients: A High-Resolution, Multi Contrast Magnetic Resonance Imaging”

MANUSKRIPTE

Freilinger T, Dimitriadis K, Nikolaou K, Reiser MF, Dichgans M, Saam T. Stroke while
squeezing a pimple: mechanical y induced rupture of an internal carotid artery plaque
causing ischemic stroke. Neurology. In press. Impact Factor 8,17

Saam T, Habs M, Cyran CC, Grimm J, Pfefferkorn T, Schül er U, Reiser MF, Nikolaou K. [New Aspects of MRI for diagnostics of large vessel vasculitis and primary angi tis of the central nervous system]. Radiologe. 2010 Oct;50(10):861-71 Impact Factor 0,48 Saam T, Habs M, Pol atos O, Cyran CC, Pfefferkorn T, Dichgans M, Dietrich O, Glaser C, Reiser MF, Nikolaou K. High-resolution black-blood contrast-enhanced T1-weighted images for the diagnosis and fol ow-up of intracranial arteritis. Br J Radiol 2010.83(993):e182-4. Impact Factor 2,366 Förster S, Rominger A, Saam T, Wolpers S, Nikolaou K, Cumming P, Reiser MF, Bartenstein P, Hacker M. 18F-fluorethylcholine uptake in arterial vessel wal s and cardiovascular risk factors: correlation in a PET-CT study. Nuklearmedizin. 2010;49(4):148-153. Impact Factor 1,87 Pfefferkorn T, Schuel er U, Cyran C, Hüfner K, Fesl G, Seelos K, Dichgans M, Pfister HW, Nikolaou K, Kretzschmar H, Saam T. Giant Cel Arteritis Confined to the Basal Cerebral Arteries: Direct Correlation of Intramural MRI Findings, Conventional Angiography and Histopathology. Neurology 2010;74(20):1651-3. Impact Factor 8,17 Saam T*, Rominger A*, Wolpers S, Nikolaou K, Rist C, Greif M, Cumming P, Becker A, Foerster S, Reiser MF, Bartenstein P, Hacker M. Association of Inflammation of the Left Coronary Artery with Cardiovascular Risk Factors, Plaque Burden and Pericardial Fat Volume: A PET/CT Study. Europ J Nucl Med and Molecular Imaging 2010;37(6):1203-12. Impact Factor 4,532 * The first two authors contributed equal y to this study Sostak P, Padovan CS, Eigenbrod S, Roeber S, Segerer S, Schankin C, Siegert S, Saam T, Theil D, Kolb HJ, Kretzschmar H, Straube A. Cerebral angi tis in four patients with chronic GVHD. Bone Marrow Transplant. 2009. Impact Factor 3,4. Rominger A, Rist C, Nikolaou K, Reiser MF, Bartenstein P, Hacker M, Saam T. [PET/CT imaging of atherosclerotic blood vessel alterations]. Radiologe 2010;37(6):1203-12. Impact Factor 0.48 Rominger A, Saam T, Vogl E, Übleis C, la Fougère, C, Förster S, Haug A, Cumming P, Reiser MF, Nikolaou K, Bartenstein P, Hacker M. In-vivo imaging of macrophage activity in the coronary arteries using 68Ga-DOTA-TATE PET/CT: correlation with coronary calcium burden and risk factors." J Nucl Med 2010;51(2):193-7. Impact Factor 6,662 Saam T, Raya JG, Cyran CC, Bochmann K, Meimarakis G, Dietrich O, Clevert DA, Frey U, Yuan C, Hatsukami TS, Werf A, Reiser MF, Nikolaou K. High Resolution Carotid Black-Blood 3T MR with Paral el Imaging and Dedicated 4-Channel Surface Coils. J Cardiovasc Magn Reson. 2009 Oct 27;11(1):41. Impact Factor 2,125 Becker CR, Saam T. Evaluation of coronary atherosclerotic plaques. Cardiol Clin. 2009 Nov;27(4):611-7. Impact Factor 0,753 Rominger A*, Saam T*, Wolpers S, Cyran CC, Schmidt M, Foerster S, Nikolaou K, Reiser MF, Bartenstein P, Hacker M. 18F-FDG PET/CT Identifies Patients at Risk for Future Vascular Events in an Otherwise Asymptomatic Cohort with Neoplastic Disease. J Nucl Med. 2009 Oct;50(10):1611-20. Impact Factor 6,662 * The first two authors contributed equal y to this study Sostak P, Saam T, Hacker M, Schankin C, Wagner J, Kolb HJ, Straube A. Large vessel vasculitis: manifestation of graft-versus-host disease? J Neurol. 2009 Impact Factor 2,536 Rist C, Johnson TR, Mül er-Starck J, Arnoldi E, Saam T, Becker A, Leber AW, Wintersperger BJ, Becker CR, Reiser MF, Nikolaou K. Noninvasive Coronary Angiography Using Dual-Source Computed Tomography in Patients With Atrial Fibril ation. Invest Radiol 2009. Impact Factor 4,234 Saam T, Oberhoffer M, Rist C, Minaifar N, Vogt F, Reichart B, Becker C, Reiser M, Nikolaou K. [Assessment of aortic stenosis after aortic valve replacement: comparative evaluation of dual-source CT and echocardiography] Rofo. 2008 Jun;180(6):553-60. Impact Factor 1,882 Underhil HR, Yuan C, Terry JG, Chen H, Espeland MA, Hatsukami TS, Saam T, Chu B, Yu W, Oikawa M, Takaya N, Yarnykh VL, Kraft R, Carr JJ, Maldjian J, Tang R, Crouse JR 3rd. Differences in carotid arterial morphology and composition between individuals with and without obstructive coronary artery disease: a cardiovascular magnetic resonance study. J Cardiovasc Magn Reson. 2008 Jun 12;10(1):31. Impact Factor 1,867 Saam T, Underhil H, Chu B, Takaya N, Cai JM, Yuan C, Hatsukami TS. Prevalence of AHA Type VI Carotid Atherosclerotic Lesions Identified by MRI for Different Levels of Stenosis as Measured by Duplex Ultrasound. J Am Coll Cardiol. 2008 Mar 11;51(10):1014-21. Impact Factor 11,054 Saam T, Schoenberg SO, Yuan C, Hatsukami TS, Reiser MF, Nikolaou K. Hochauflösende Bildgebung Magnetresonanztomographie. Review. Rofo. 2008 Feb;180(2):100-11. Impact Factor 1,882 Underhil HR, Yuan C, Zhao XQ, Kraiss LW, Parker DL, Saam T, Chu B, Takaya N, Liu F, Polissar NL, Neradilek B, Raichlen JS, Cain VA, Waterton JC, Hamar W, Hatsukami TS. Effect of rosuvastatin therapy on carotid plaque morphology and composition in moderately hypercholesterolemic patients: a high-resolution magnetic resonance imaging trial. Am Heart J. 2008 Mar;155(3):584.e1-8.Impact Factor 3,649 Kerwin W, Xu D, Liu F, Saam T, Underhil H, Takaya N, Chu B, Hatsukami T, Yuan C. Magnetic resonance imaging of carotid atherosclerosis: plaque analysis. Top Magn Reson Imaging. 2007 Oct;18(5):371-8. Impact Factor Saam T, Hatsukami TS, Yarnykh VL, Hayes CE, Underhil H, Chu B, Takaya N, Cai J, Kerwin WS, Xu D, Polissar NL, Neradilek B, Hamar WK, Maki J, Shaw DW, Buck R, Wyman B, Yuan C. Reader- and Platform Reproducibility for Quantitative Assessment of Carotid Atherosclerotic Plaque Using 1.5T Siemens, Philips and GE Scanners. J Magn Reson Imaging. 2007 Aug;26(2):344-52. Impact Factor: 2,637 Nikolaou, K, Saam T, Rist, K, Johnson T, Vogt F, Oberhoffer M, Reichart B, Reiser MF, Becker CR. Einsatz der Dual-Source Computertomographie in der prä- und postoperativen kardiochirurgischen Diagnostik. Radiologe. 2007 Apr;47(4):310-8. German. Impact Factor: 0,696 Yuan C, Kerwin WS, Yarnykh VL, Cai J, Saam T, Chu B, Takaya N, Ferguson MS, Underhil H, Xu D, Liu F, Hatsukami TS. MRI of atherosclerosis in clinical trials. NMR Biomed. 2006 Oct;19(6):636-54. Impact Factor: 3,626 Saam T, Hatsukami TS, Takaya N, Chu B, Underhil H, Kerwin WS, Cai JM, Ferguson MS, Yuan C. Noninvasive Magnetic Resonance Imaging of the Vulnerable / High-Risk Atherosclerotic Plaque. Radiology. 2007 Jul;244(1):64-77. Impact Factor: 5,251 Saam T, Yuan C, Chu B, Takaya N, Underhil H, Cai J, Tran N, Polissar NL, Neradilek B, Jarvik GP, Isaac C, Garden GA, Maravil a KR, Hashimoto B, Hatsukami TS. Predictors of Carotid Atherosclerotic Plaque Progression as Measured by Noninvasive Magnetic Resonance Imaging. Atherosclerosis. 2007 Oct;194(2):e34-42. Impact Factor: 3,811 Saam T, Cai JM, Ma L, Cai YQ, Ferguson MS, Polissar NL, Hatsukami TS, Yuan C. Comparison of Symptomatic and Asymptomatic Atherosclerotic Carotid Plaque Features Using in vivo MRI. Radiology. 2006 Aug;240(2):464-72. Impact Factor: 5,251
Takaya N, Yuan C, Chu B, Saam T, Underhil H, Cai J, Tran N, Polissar NL, Isaac C,
Ferguson MS, Garden GA, Cramer SC, Maravil a KR, Hashimoto B, Hatsukami TS.
Association between carotid plaque characteristics and subsequent ischemic
cerebrovascular events: a prospective assessment with MRI--initial results. Stroke. 2006
Mar;37(3):818-23. Impact Factor: 5,391

Liu F, Xu D, Ferguson MS, Chu B, Saam T, Takaya N, Hatsukami TS, Yuan C, Kerwin WS.
Automated in vivo Segmentation of Carotid Plaque MRI with Morphology-Enhanced
Probability Maps. Magn Reson Med. 2006 Mar;55(3):659-68. Impact Factor: 3,427

Takaya N, Cai J, Ferguson MS, Chu BC, Saam T, Polissar NL, Hatsukami TS, Yuan C.
Reproducibility of magnetic resonance imaging for quantifying the lipid rich necrotic core is
improved with gadolinium contrast enhancement. J Magn Reson Imaging. 2006
Jul;24(1):203-10. Impact Factor: 2,47

Saam T, Kerwin WS, Chu B, Cai JM, Kampschulte A, Hatsukami TS, Zhao XQ, Polissar NL,
Yarnykh VL, Flemming K, Huston J, Insul W, Morrisett J, Rand S, DeMarco K, Yuan C.
Sample Size Calculation for Clinical Trials Using Magnetic Resonance Imaging for the
Quantitative Assessment of Carotid Atherosclerosis. J Cardiovasc Magn Reson.
2005;7(5):799-808. Impact Factor: 1,739

Cai JM, Hatsukami TS, Ferguson MS, Kerwin WS, Saam T, Chu BC, Takaya N, Polissar NL,
Yuan C. In Vivo Quantitative Measurement of Intact Fibrous Cap and Lipid Rich Necrotic
Core Size in Atherosclerotic Carotid Plaque: A Comparison of High Resolution Contrast
Enhanced MRI and Histology. Circulation. 2005 Nov 29;112(22):3437-44. Impact Factor:
11,632

Saam T, Hess T, Kasperk C, Kauffmann GW, Düx M. Prävalenz der latenten und manifesten
Hyperthyreose in einem Jodmangelgebiet: Erhebung an einem nicht-selektionierten
Patientenkol ektiv vor Durchführung einer Computertomographie mit jodhaltigem
Kontrastmittel. Rofo. 2005 Sep;177(9):1250-4. Impact Factor: 1,908
Takaya N, Yuan C, Chu BC, Saam T, Polissar NL, Isaac C, McDonough J, Ferguson MS,
Hatsukami TS. Presence of intraplaque hemorrhage stimulates progression of carotid
atherosclerotic plaques: a high-resolution magnetic resonance imaging study. Circulation.
2005 May 31;111(21):2768-75. Impact Factor: 11,632

Chu B, Zhao XQ, Saam T, Yarnykh VL, Kerwin WS, Flemming KD, Huston J 3rd, Insul W
Jr, Morrisett JD, Rand SD, DeMarco KJ, Polissar NL, Balu N, Cai J, Kampschulte A,
Hatsukami TS, Yuan C. Feasibility of in vivo, multicontrast-weighted MR imaging of carotid
atherosclerosis for multicenter studies. J Magn Reson Imaging. 2005 Jun;21(6):809-17.
Impact Factor: 2,47

Saam T, Cai JM, Cai YQ, An NY, Kampschulte A, Xu D, Kerwin WS, Polissar NL, Hatsukami
TS, Yuan C. Carotid Plaque Composition differs between Ethno-Racial Groups: An MRI Pilot
Study comparing Mainland Chinese and American Caucasian Patients. Arterioscler Thromb
Vasc Biol. 2005 Mar;25(3):611-6. Impact Factor: 7,053

Saam T, Ferguson MS, Yarnykh VL, Xu D, Polissar NL, Hatsukami TS, Yuan C. Quantitative
Evaluation of Carotid Plaque Composition by in vivo MRI. Arterioscler Thromb Vasc Biol.
2005 Jan;25(1):234-9. Impact Factor: 7,053

Kampschulte A, Ferguson MS, Kerwin WS, Polissar NL, Chu C, Saam T, Hatsukami TS,
Yuan C. Differentiation of Intraplaque Versus Juxtaluminal Hemorrhage/Thrombus in
Advanced Human Carotid Atherosclerotic Lesions by in vivo MRI. Circulation. 2004 Nov
16;110(20):3239-44. Impact Factor: 12,563

Grenacher L, Saam T, Geier A, Mül er-Hülsbeck S, Cejna M, Kauffmann GW, Richter GM.
PTA versus Stent bei Stenosen der A. Femoralis und A. Poplitea: eine prospektive
randomisierte Multizenterstudie (REFSA). Rofo. 2004 Sep;176(9):1302-10. Impact Factor:
1,767

Saam T, Ehmke H, Ritz E, Amann K. The Effect of Endothelin Blockade on Cardiovascular
Remodel ing in the one Clip – two Kidney Hypertension of the Rat. Kidney Blood Press Res.
2003; 26(5-6):325-32. Impact Factor: 1,025

VORTRÄGE

Saam T, Cyran C, Habs M, Pfefferkorn T, Dichgans M, Dietrich O, Reiser MF, Nikolaou K.
Hochaufgelöste Black-Blood 3T MRT in der Diagnostik der Primären Vaskulitis des
Zentralen Nervensystems. Deutscher Röntgenkongress 2010, May 12th-15th, Berlin,
Germany, RöFo; S 1, 2010, Volume 182, VO_201.6 (Neuro I – Nicht-Ischämische
Erkrankungen I)

Saam T, Rominger A, Wolpers S, Rist C, Greif M, Cumming PK, Becker A, Foerster S,
Reiser MF, Bartenstein P, Hacker M, Nikolaou K. Assoziation entzündlicher Veränderungen
der linken Koronararterie mit kardiovaskulären Risikofaktoren, atherosklerotischer Plaquelast
und dem Volumen des perikardialen Fettgewebes: Eine PET/CT-Studie. Deutscher
Röntgenkongress 2010, May 12th-15th, Berlin, Germany, RöFo; S 1, 2010, Volume 182,
VO_202.1 (Gefäße I – Methodenvergleich)
Saam T, Rominger A, Wolpers S, Cyran CC, Reiser MF, Bartenstein P, Hacker M, Nikolaou
K. Korrelation der arteriel en F18-FDG Aufnahme und der Atherosklerotischen Plaquelast mit
dem Auftreten von kardio- und zerebrovaskuären Ereignissen: Eine PET-CT Studie.
Deutscher Röntgenkongress 2010, May 12th-15th, Berlin, Germany, RöFo; S 1, 2010, Volume
182, VO_202.2 (Gefäße I – Methodenvergleich)
Saam T, Pfefferkorn T, Habs M, Hacker M, Rominger A, Cyran C, Dichgans M, Reiser MF, Nikolaou K. Age of vessel wal hematoma in cervical artery dissection as determined by multi-sequence MRI. European Congress of Radiology 2010, March 4th-8th, Vienna, Austria. ECR 2010 Vol 1, S1,B-436 Saam T, Pfefferkorn T, Habs M, Hacker M, Rominger A, Cyran C, Dichgans M, Reiser MF, Nikolaou K. Spontaneous cervical artery dissection: an inflammatory disease? Results of a prospective observational PET-CT and MRI study. European Congress of Radiology 2010, March 4th-8th, Vienna, Austria. ECR 2010 Vol 1, S1,B-658 Saam T, Rominger A, Wolpers S, Bartenstein P, Hacker M, Reiser M, Nikolaou K. Association of Inflammation of the Left Coronary Artery with Cardiovascular Risk Factors, Plaque Burden and Pericardial Fat Volume: A PET/CT Study. 95th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Chicago, USA, November 29th – December 4th, 2009, SST02-08 Saam T, Rominger A, Wolpers S, Cyran C, Bartenstein P, Hacker M, Nikolaou K. Increased Arterial Wal 18F-FDG-Uptake is Associated with Future Cardiovascular Events: A PET-CT Study Considering Age and Cardiovascular Risk Factors. European Congress of Radiology 2009, March 6th-10th, Vienna, Austria. ECR 2009 Vol 19, S1, NH 9 Saam T, Cyran C, Sourbron S, Raya JG, Bochmann K, Hacker M, Rominger A, Bartenstein P, Pfefferkorn T, Dichgans M, Werf TA, Gerhards H, Reiser MF, Nikolaou K. Die kontrastverstärkte, dynamische MRT zur Quantifikation der Entzündung von Arterienwänden in Korrelation zur 18F-FDG PET-CT. Meeting der Experimentellen Radiologie, Mainz, Germany, February 12th-13th Saam T, Underhil HR, Chu B, Takaya N, Cai J, Nikolaou K, Reiser MF, Hatsukami TS. The
Impact of Arterial Remodeling on the Occurrence of Complicated Plaque Features: An in
vivo MRI study. 94th Scientific Assembly and Annual Meeting of the Radiological Society of
North America, Chicago, USA, November 30th – December 5, 2008, SSQ14-06

Saam T, Rominger A, Wolpers S, Cyran C, Nikolaou K, Bartenstein P, Hacker M. Increased
Arterial Wal 18F-FDG-Uptake is Associated with Future Cardiovascular Events: A PET-CT
Study Considering Age and Cardiovascular Risk Factors. 90th Scientific Assembly and
Annual Meeting of the Radiological Society of North America, Chicago, USA, December 1st –
December 5, 2008, SSG11-02

Saam T, Underhil HR, Chu B, Takaya N, Cai J, Nikolaou K, Reiser MF, Hatsukami TS.
Nicht-invasive Darstel ung des arteriel en Remodeling und dessen Einfluss auf die Prävalenz
vulnerabler atherosklerotischer Karotisplaques mit der Magnetresonanztomographie.
Deutscher Röntgenkongress 2008, May 20th-20rd, Berlin, Germany, RöFo; S 1, 2008,
Volume 180, VO_220.7 (Gefäße II –Dissektion und Plaque)
Saam T, Raya JG, Bochmann K, Meimarakis G, Sourbron S, Frey U, Werf A, Gerhards H,
Reiser MF, Nikolaou K. High Resolution Carotid Black Blood 3T MRI with Paral el Imaging:
Initial Experience. European Congress of Radiology 2008, March 7th-11th, Vienna, Austria.
ECR 2008 Vol 18 Suppl. 1, B-068
Saam T, Oberhoffer M, Rist C, Minaifar N, Vogt F, Reichart B, Becker CR, Reiser MF,
Nikolaou K. Assessment of Aortic Stenosis after aortic valve replacement: Comparative
Evaluation of Dual-Source CT and Echocardiography. European Congress of Radiology
2008,March 7th-11th, Vienna, Austria. ECR 2008 Vol 18 Suppl. 1, B-826
Saam T, Underhil HR, Chu B, Takaya N, Cai J, Nikolaou K, Reiser MF, Hatsukami TS. The
Impact of Arterial Remodeling on the Occurrence of Complicated Plaque Features: An in
vivo MRI study. Scientific Sessions of the American Heart Association 2007, November 4-7
Circulation 2007; 116(16):II-561-2541

Saam T; Nikolaou K, Oberhoffer M, Reichart B, Reiser MF, Becker CR. Quantitative
Evaluation der Aortenklappenöffnungsfläche mit Dual-Source CT und Korrelation mit der 2D-
Echokardiographie: Initiale Ergebnisse. 87. Deutscher Röntgenkongress, Berlin, Germany,
May 16-19, 2007. RöFo; S 1, 2007, Volume 179, VO_208.7 (Herz II –Dual Source CT des
Herzens-Technische Aspekte)
Saam T; Underhil HR, Chu B, Takaya N, Cai J, Yuan C, Hatsukami TS. Evaluierung der
Prävalenz Vulnerabler Atherosklerotischer Karotisplaques in Patienten mit unterschiedlichem
Stenosegrad der Karotiden mit der nichtinvasiven Magnetresonanztomographie. 87.
Deutscher Röntgenkongress, Berlin, Germany, May 16-19, 2007. RöFo; S 1, 2007, Volume
179, VO_318.2 (Gefäße III – Neue Ansätze in der Gefäßdiagnostik)
Saam T; Underhil HR, Chu B, Takaya N, Cai J, Yuan C, Hatsukami TS. Prevalence of AHA
Type VI Carotid Atherosclerotic Lesions Identified by MRI for Different Levels of Stenosis as
Measured by Duplex Ultrasound. European Congress of Radiology 2007, Vienna, Austria.
ECR 2007, S1, Volume 17, B-188
Saam T, Hatsukami TS, Underhil H, Chu B, Takaya N, Cai J, Yarnykh VL, Kerwin WS, Yuan
C. Sind quantitative Messungen Atherosklerotischer Plaques mittels 1.5T Siemens-, GE-
und Phil ips MR-Tomographen identisch? 86. Deutscher Röntgenkongress, Berlin, Germany,
May 24-27, 2006. RöFo; S 1, 2006, Volume 178, VO_323.9 (Gefäße II –Kopf, Aorta,
Plaque)

Saam T, Yuan C, Chu B, Takaya N, Underhil H, Cai J, Tran N, Polissar NL, Neradilek B,
Jarvik GP, Isaac C, Garden GA, Maravil a KR, Hashimoto B, Hatsukami TS. Predictors of
Carotid Atherosclerotic Plaque Progression as Measured by Noninvasive Magnetic
Resonance Imaging. Scientific Sessions of the American Heart Association 2005, November
13-16. Circulation 2005; 112(17):II-643-3033

Saam T, Hatsukami TS, Underhil H, Chu B, Takaya N, Cai J, Yarnykh VL, Kerwin WS, Xu
D, Polissar NL, Hamar WK, Maki J, Shaw D, Buck R, Wastal P, Mychajluk M, Yuan C.
Atherosclerotic Plaque Tissue Quantitation Considerations of Inter-Scan and Inter-Platform
Variability. 17th Annual international conference on magnetic resonance angiography: MR
Angio Club, Beijing, China, September 21-23, 2005, Talk #6.6

Saam T, Ferguson MS, Yarnykh VL, Xu D, Polissar NL, Hatsukami TS, Yuan C.
Identifizierung und Quantifizierung von arteriosklerotischen Plaquekomponenten der Arteria
Carotis mittels nichtinvasiver MRT. 86. Deutscher Röntgenkongress, Berlin, Germany, May
4-7, 2005. RöFo; S 1, 2005, Volume 177, VO_4005 (Gefäßdiagnostik III -Karotis)

Saam T, Ferguson MS, Hatsukami TS, Yuan C. Identification of Smooth Juxtaluminal Layers
of Loose Fibrous Matrix with Magnetic Resonance Imaging as an Indicator of Healed
Rupture in Symptomatic and Asymptomatic Carotid Disease. 90th Scientific Assembly and
Annual Meeting of the Radiological Society of North America, Chicago, USA, November 28 –
December 3, 2004, SSK15-04

Saam T, Takaya N, Polissar NL, Hatsukami TS, Yuan C. Identification of Early Hemorrhage
with Magnetic Resonance Imaging is Highly Associated with Markers of Plaque Vulnerability
and Patients’ Symptom Status. Scientific Sessions of the American Heart Association 2004,
October 7-10. Circulation 2004; 110(17):III-248-1189

Saam T, Ferguson MS, Yarnykh VL, Xu D, Polissar NL, Hatsukami TS, Yuan C. Accuracy of
In Vivo Quantitative Characterization of Atherosclerotic Carotid Plaque: A High-Resolution,
Multi Contrast Magnetic Resonance Imaging Study.7th Annual Meeting for Cardiovascular
Magnetic Resonance, February 13-15, 2004, 04-348-SCMR, J Cardiovasc Magn
Resonance, Vol. 6, No.1, pp.43-101, 2004 (159)

EINGELADENE VORTRÄGE
Saam T. Carotid plaque imaging is crucial for CAS or CEA. CIRSE 2010, SS 2702, Valencia,
Spain.
Saam T. Plaque Imaging und Bildgebung des Aortenbogens: Diagnostischer Stel enwert.
Fortbildungsveranstaltung
Schlaganfallszentrums der Universität München, Germany, 2010 March 13 Saam T. In Vivo Molecular Imaging of Vasculitis and Atherosclerosis. 2nd Interdisciplinary Summit on Inflammation, Molecular Imaging in Infection, Inflammation and Beyond,Munich, Germany, 2010 March 12. Session 52 Saam T. Hochaufgelöste Magnetresonanztomographie des Vulnerablen Atherosklerotischen Plaques. Arbeitskreis Gefäßmedizin, München, 2009, April 23rd Saam T. High-resolution Magnetic Resonance Imaging of the Carotid Artery at 3.0T. 13th International MRI Symposium, Garmisch-Partenkirchen, 2009, January 22nd- 24th. Saam T. Aussagen der Schnittbilddiagnostik zum Stenosegrad und zur Plaquemorphologie. Neurologisches Kol oquium, München, 2008, June 25th Saam T. Hochaufgelöste MRT-Bildgebung Atherosklerotischer Gefäßwandläsionen der Karotiden. Jahrestagung der Angiologen, München, 2007 Saam T, Nikolaou K, Schoenberg SO, Yuan C, Hatsukami TS, Reiser MF. High-resolution plaque imaging of the carotids at 1.5T and 3.0T. 12th International MRI Symposium, Garmisch-Partenkirchen, 2007, February 1-3.
Saam T, Nikolaou K, Yuan C, Hatsukami TS, Reiser MF. Noninvasive Magnetic Resonance
Imaging of the Vulnerable/High-Risk Carotid Atherosclerotic Plaque. 7 th World Congress on
Trauma, Shock, Inflammation and Sepsis, Munich, Germany, 2007 March 13-17. Session
96, SY 833.

CHAIRMAN / MODERATOR
New Horizons Session “Plaque Imaging” NH9 European Congress of Radiology 2009, March
6th-10th, Vienna, Austria. ECR 2009 Vol 18 Suppl. 1, A194 - A198
Bildgebung der Atherosklerose. Jahrestagung der Angiologen, München, 2007

PEER REVIEWER & MITGLIEDSCHAFTEN
Member “Deutsche Röntgengesel schaft” since 08/2001
Member „Marburger Bund“ since 06/1999
Member “American Heart Association” since 01/2006
Member „Radiological Society of North America” since 08/2006
Member “European Society of Radiology” since 02/2007
Reviewer Arteriosclerosis, Thrombosis & Vascular Biology since 1/2004
Reviewer Journal of Magnetic Resonance Imaging since 5/2004
Reviewer Circulation since 1/2004
Grant Reviewer FONDAZIONE CARIVERONA in 2007
Reviewer Neuroradiology since 06/2007
Reviewer International Journal of Computed Assisted Radiology and Surgery since 03/2008
Reviewer Investigative Radiology since 06/2008
Reviewer American Journal of Radiology since 06/2008
Reviewer Biomarkes in Medicine since 08/2008
Reviewer Circulation: Cardiovascular Imaging since 08/2008
Reviewer RoeFo since 9/2009

BUCHKAPITEL
Saam T, Kerwin WS, Yuan C. Vascular Imaging. Encyclopedia of Biomaterials and
Biomedical Engineering 2004. DOI: 10.1081/E-EBBE-120013985. ISBN: 0-8247-4789-4,
Marcel Dekker Inc. Edited by: Gary E. Wnek and Gary L. Bowlin

KOMMENTARE & ZEITSCHRIFTEN
Saam T, Ho AA, Yuan C. Atherosclerotic Plaque Characterization across Different Ethno-
Racial Groups Using Noninvasive Magnetic Resonance Imaging. International
Atherosclerosis Society, April 2005. www.athero.org

Saam T, Reiser MF, Nikolaou K. Imaging of the Carotid Atherosclerotic Plaque with 3T MRI
Using dedicated 4-Channel Surface Coils. Siemens FLASH Magazine 2009

POSTER

Habs M, Pfefferkorn T, Habs M, Hacker M, Rominger A, Cyran C, Dichgans M, Reiser MF,
Nikolaou K, Saam T. Spontane arteriel e Dissektionen der Halsgefäße: eine entzündliche
Erkrankung? Ergebnisse einer prospektiven MRT- und PET/CT-Untersuchung. Deutscher
Röntgenkongress 2010, May 12th-15th, Berlin, Germany, RöFo; S 1, 2010, Volume 182,
VO_210.3 (Gefäße II – Methodenvergleich II)

Saam T, Pfefferkorn T, Habs M, Hacker M, Rominger A, Cyran C, Dichgans M, Reiser MF,
Nikolaou K. Spontaneous cervical artery dissection: an inflammatory disease? Results of a
prospective observational PET-CT and MRI study. ISMRM 2010, Stockholm, Sweden.
Poster
Cyran CC, Saam T, Sourbron S, Raya J, Reiser MF, Nikolaou K. "Quantification of Arterial
Wal Inflammation in Patients with Arteritis Using High-Resolution DCE-MRI and 18F-FDG
PET-CT: A Correlation Study". 95th Scientific Assembly and Annual Meeting of the
Radiological Society of North America, Chicago, USA, November 29th – December 4th, 2009,
SSC09-02

Saam T, Habs M, Pol atos O, Cyran CC, Pfefferkorn T, Dichgans M, Dietrich O, Glaser C,
Reiser MF, Nikolaou K. High-resolution black-blood contrast-enhanced T1-weighted images
for the diagnosis and fol ow-up of intracranial arteritis. ISMRM 2009, Hawaii, USA. E-Poster

Clevert DA, Saam T, Sommer W, Reiser MF. The use of contrast-enhanced ultrasound for
the characterization of neovascularization in carotid atherosclerotic plaques. European
Congress of Radiology 2009, March 6th-10th, Vienna, Austria. ECR 2009 Vol 19, S1, B-026
Clevert DA, Saam T, Horng A, Reiser M. The Use of Contrast-Enhanced Ultrasound in
Characterization of Neovascularization in Carotid Atherosclerotic Plaque. American Journal
of Roentgenology 2009, Volume: 192 Issue: 5 Supplement: Suppl. S, 436BI
Cyran C, Saam T, Sourbron S, Raya JG, Bochmann K, Hacker M, Rominger A, Bartenstein
P, Pfefferkorn T, Dichgans M, Werf TA, Gerhards H, Reiser MF, Nikolaou K. Quantification
of arterial wal inflammation in patients with arteri ts using highresolution DCE-MRI:
Correlation with 18F-FDG PET-CT. European Congress of Radiology 2009, March 6th-10th,
Vienna, Austria. ECR 2009 Vol 19, S1, B-070
Rominger A, Saam T, Wolpers S, Cyran C, Schmidt M, Nikolaou K, Bartenstein P, Hacker
M. [18F]-Fluorodeoxyglucose PET-CT identifies patients at risk for future cardiovascular
events in an otherwise asymptomatic cohort suffering from neoplastic disease. SNM 2009
Prämiert mit dem Young Investigator Award
Berger F, Schlemmer M, Saam T, Nikolaou K, Becker C, Reiser MF. Perfusions-CT zum
Monitoring spezifischer molekularer Pharmakotherapie bei Patienten mit metastasiertem
Gastrointestinalen Stromatumor. Deutscher Röntgenkongress 2008, May 20th-20rd, Berlin,
Germany, RöFo; S 1, 2007, Volume 180, VO_412.2 (Gastrointestinales System V –
Intestinaltrakt II)

Saam T, Rominger A, Wolpers S, Cyran C, Nikolaou K, Bartenstein P, Hacker M. Increased
Arterial Wal 18F-FDG-Uptake Identifies Patients at Risk for Future Cardiovascular Events: A
PET-CT Study Considering Age and Cardiovascular Risk Factors. Scientific Sessions of the
American Heart Association 2008, November 8-12, Circulation 2008; 118(18):S1009-5814

Saam T, Rominger A, Wolpers S, Cyran C, Nikolaou K, Bartenstein P, Hacker M. Increased
Arterial Wal 18F-FDG-Uptake Identifies Patients at Risk for Future Cardiovascular Events: A
PET-CT Study Considering Age and Cardiovascular Risk Factors. 3rd International
Symposium “Integrated Biomarkers in Cardiovascular Diseases”, Seattle, WA, USA, 2008
July 9th-11th
Rominger A, Saam T, Wolpers S, Cyran C, Schmidt M, Nikolaou K, Bartenstein P, Hacker
M. Increased arterial 18F-FDG-uptake is highly associated with future Cardiovascular
Events: a PET-CT Study considering Age and Cardiovascular Risk Factors. EANM Oktober
2008
Saam T, Cyran C, Sourbron S, Raya JG, Bochmann K, Hacker M, Rominger A, Bartenstein
P, Pfefferkorn T, Dichgans M, Werf TA, Gerhards H, Reiser MF, Nikolaou K. Quantification
of Arterial Wal Inflammation Using Dynamic Contrast Enhanced MRI: Correlation with 18F-
FDG PET-CT. 3rd International Symposium “Integrated Biomarkers in Cardiovascular
Diseases”, Seattle, WA, USA, 2008 July 9th-11th
Berger F, Schlemmer M, Saam T, Nikolaou K, Becker C, Reiser MF. Perfusion CT in the
fol ow-up of patients with gastrointestinal stromal tumors under specific molecular
pharmacotherapy. European Congress of Radiology 2008, March 7th-11th, Vienna, Austria.
ECR 2008 Vol 18 Suppl. 1, B-014

Oikawa M, Yuan C, Underhil HR, Zhao XQ, Kraiss LW, Parker DL, Saam T, Chu B, Takaya
N, Fei L, Polissar NL, Neradilek B, Raichlen JS, Cain VA, Waterton JC, Hamar W,
Hatsukami TS. Time Course of Change in Plaque Composition Associated with Rosuvastatin
Therapy as Assessed by High-Resolution Magnetic Resonance Imaging. Scientific Sessions
of the American Heart Association 2007, November 4-7, Circulation 2007; 116(16):II-411-
1912

Saam T; Underhil HR, Chu B, Takaya N, Cai J, Yuan C, Hatsukami TS. Distribution of AHA
Type VI Atherosclerotic Lesions in the Carotid Artery and Relationship to Quantitative Plaque
Measurements: An in vivo MRI Study. ISMRM-ESMRMB Meeting, Berlin, Germany, May
19th-25th. PO-3102.
Underhil HR, Hatsukami TS, Raichlen J, Waterton J, Liu F, Kerwin WS, Saam T, Chu B,
Takaya N, Zhao X, Hamar W, Yuan C. Morphology-enhanced probabilistic plaque
segmentation identifies regression of the lipid rich portion of carotid plaques after 2 years of
Rosuvastatin therapy. Scientific Sessions of the American Heart Association 2006,
Circulation Suppl 2006; 114(18):II-377-378 (1899)
Saam T, Underhil H, Chu B, Takaya N, Cai J, Yuan C, Hatsukami TS. Prevalence of AHA
Type VI Carotid Atherosclerotic Lesions Identified by MRI for Different Levels of Stenosis as
Measured by Duplex Ultrasound. Scientific Sessions of the American Heart Association
2006, Circulation Suppl 2006; 114(18):II-776 (3635)

Saam T, Yuan C, Chu B, Takaya N, Underhil H, Cai J, Tran N, Polissar NL, Hatsukami TS.
Einfluss von Risikofaktoren auf die Progression Atherosklerotischer Plaques in der A.
Karotis: Eine nichtinvasive MRT-Studie. 86. Deutscher Röntgenkongress, Berlin, Germany,
May 24-27, 2006. RöFo; S 1, 2006, Volume 178, WI_PO 19 (Gefäße)
Saam T, Hatsukami TS, Underhil H, Chu B, Takaya N, Cai J, Yarnykh VL, Kerwin WS, Xu
D, Polissar NL, Hamar WK, Maki J, Shaw DW, Buck R, Wastal P, Mychajluk M, Wyman B,
Yuan C. Intra- and Inter-Platform Reproducibility of 1.5T Siemens, GE and Phil ips Scanners
for Quantitative Assessment of Carotid Atherosclerotic Plaque. 9th Annual SCMR Scientific
Sessions Miami, FL, USA, January 20-22, 2006; J Cardiovasc Magn Resonance, Vol. 8,
No.1, pp.137-138, 2006 (343)
Saam T, Hatsukami TS, Underhil H, Chu B, Takaya N, Cai J, Yarnykh VL, Kerwin WS, Xu
D, Polissar NL, Hamar WK, Maki J, Shaw DW, Buck R, Wastal P, Mychajluk M, Wyman B,
Yuan C. “Intra- and Inter-Platform Reproducibility of 1.5T Siemens, GE and Phil ips
Scanners for Classifying Carotid Atherosclerotic Lesion Type Using Modified AHA Criteria”.
9th Annual SCMR Scientific Sessions Miami, FL, USA, January 20-22, 2006; J Cardiovasc
Magn Resonance, Vol. 8, No.1, p.286, 2006 (524)

Chu B, Balu N, Underhil H, Saam T, Takaya N, Raichlen J, Waterton J, Hatsukami TS,
Yuan C. “Carotid Magnetic Resonance Scans provide consistent signal-to-noise ratio and
contrast-to-noise ratio in the ORION trial”. 9th Annual SCMR Scientific Sessions Miami, FL,
USA, January 20-22, 2006; J Cardiovasc Magn Resonance, Vol. 8, No.1, pp.143-145, 2006
(349)

Saam T, Cai J, Cai YQ, Ma L, Ferguson MS, Polissar NL, Hatsukami TS, Yuan C.
Nichtinvasives MRT differenziert zwischen symptomatischen und asymptomatischen
arteriosklerotischen Plaques der Karotiden. 86. Deutscher Röntgenkongress, Berlin,
Germany, May 4-7, 2005; RöFo; S 1, 2005, Volume 177, PO_69 (Gefäße)

Saam T, Yuan C, Zhao XQ, Takaya N, Underhil H, Chu B, Cai JM, Kerwin WS, Kraiss LW,
Parker DL, Hamar W, Waterton J, Cain V, Raichlen J; Hatsukami TS. Assessment of
Rosuvastatin Treatment on Carotid Atherosclerosis in Moderately Hypercholesterolemic
Subjects Using High-Resolution Magnetic Resonance Imaging. 75th Meeting of the European
Atherosclerosis Society, Prag, Czech Republic, May 12-15, 2005, W17-LMP-005

Saam T, Kerwin WS, Chu B, Cai J, Kampschulte A, Hatsukami TS, Zhao XQ, Polissar NL,
Yarnykh VL, Flemming K, Huston III J, Insul Jr W., Morrisett JD, Rand SD, DeMarco KJ,
Yuan C. Interscan Reproducibility of Quantitative Plaque Measurements of Carotid
Atherosclerosis in a Clinical Multi-Center Trial using Magnetic Resonance Imaging. 8th
Annual SCMR Scientific Sessions San Francisco, CA, USA, January 21-23, 2005. J
Cardiovasc Magn Resonance, Vol. 7, No.1, pp.132-133, 2005 (355)
Chu B, Zhao XQ, Saam T, Yarnykh VL, Kersin WS, Flemming KD, Huston J, Insul W, Jr,
Morrisett JD, Rand SD, DeMarco KJ, Polissar NL, Cai JM, Kamschulte A, Hatsukami TS,
Yuan C. Feasibility of in vivo, multi-contrast weighted MR imaging of carotid atherosclerosis
for multi-center studies. 8th Annual SCMR Scientific Sessions San Francisco, CA, USA,
January 21-23, 2005; J Cardiovasc Magn Reson 2005; 7(1): 142. #367.

Takaya N, Yuan C, Chu, BC, Saam T, Polissar N, Isaac C, McDonough J, Ferguson M,
Hatsukami TS. Signal Intensity Change of Carotid Intraplaque Hemorrhage; A long Term
Fol ow Up In Vivo MRI Study. 8th Annual SCMR Scientific Sessions San Francisco, CA, USA,
January 21-23, 2005; J Cardiovasc Mgn Resonance, Vol. 7, No. 1, pp. 139-140, 1005 (363).

Saam T, Polissar NL, Hatsukami TS, Yuan C. Quantitative and Morphological Assessment
of Carotid Atherosclerotic Plaque Symmetry Using Noninvasive Magnetic Resonance
Imaging. 32nd Annual Meeting & Scientific Sessions of the North American Society for
Cardiac Imaging, Amelia Island, Florida, USA, October 2–5, 2004, P#141

Takaya N, Yuan C, Chu BC, Saam T, Polissar NL, Isaac C, McDonough J, Ferguson MS,
Hatsukami TS. Presence of Intraplaque Hemorrhage Affects Progression of Carotid
Atherosclerotic Plaques: A High-Resolution Magnetic Resonance Imaging study. Scientific
Sessions of the American Heart Association 2004, New Orleans, USA, November 7–10,
2004; P#1774 ; Circulation 2004; 110(17):III-372
Xu D, Kerwin WS, Saam T, Ferguson MS, Yuan C. CASCADE: Computer Aided System for
Cardiovascular Disease Evaluation. ISMRM Annual Meeting 2004; Kyoto, Japan. #1922.

Saam T, Ferguson MS, Yarnykh VL, Hatsukami TS, Yuan C. Carotid Atherosclerotic Plaque
Composition has a Direct Impact on Plaque Burden and Lumen Narrowing. 29th International
Stroke Conference, San Diego, USA, February 5-7, 2004; P-280

Saam T, Cai JM, Cai YQ, An NY, Kampschulte A, Xu D, Kerwin WS, Polissar NL, Hatsukami
TS, Yuan C. A High-Resolution, Multi Contrast Magnetic Resonance Imaging (MRI) study for
the Evaluation of differences of the Carotid Atherosclerotic Plaque between symptomatic
Chinese and American patients. Atherosclerosis Supplements, Volume 4, Issue 2, 2003,
Page 116; 2P-0354

Cai JM, Saam T, Cai YQ, Ma L, Polissar NL, Hatsukami TS, Yuan C. Differences in Carotid
Artery Atherosclerotic Lesion Characteristics from the Index- and Non-index Side of
Symptomatic Patients: A High-Resolution, Multi Contrast Magnetic Resonance Imaging
(MRI) Study. Atherosclerosis Supplements, Volume 4, Issue 2, 2003, Page 150; 2P-0502

Saam T, Grenacher L, Geier A, Mül er-Hülsbeck S, Cejna M, Kauffmann GW, Richter G.
PTA versus Stent bei Stenosen der A. Femoralis und A. Poplitea: eine prospektive
randomisierte Multizenterstudie (REFSA). 84. Deutscher Röntgenkongress, May 28-31,
2003, Wiesbaden, ID 489
Saam T, Hess T, Lubienski A, Kauffmann GW, Düx M. The prevalence of latent
hyperthyreosis in a non-selected patient col ective admitted for CT studies. European
Congress of Radiology, Wien, Austria, March 7-11, 2003, C-0422

Saam
Endothelinrezeptorantagonisten auf kardiovaskuläre Veränderungen im Schädigungsmodel des renovaskulären Hypertonus im Vergleich mit Angiotensin-Converting-Enzym-Hemmern. 32. Kongress der Gesellschaft für Nephrologie, Münster, Germany, September 29 – October 2, 2001, P 256

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