What it is:
A highly effective and advanced non-ablative, non-surgical laser treatment designed to
target aging and damaged skin by creating microscopic “wounds” within the targeted areas of
the skin trigger collagen production and reverse the signs of aging.
Ideal for treating age spots, brown spots, acne scars, surgical scars and wrinkles
around the eyes the Fraxel
® Laser Treatment also improves skin texture and tone and
minimizes pore size.

Fraxel® is generally performed on the face, neck, décolleté, arms and hands. Features & Benefits:
• Combines the impact of ablative lasers with the gentleness of non-ablative lasers so
healing occurs quickly with little down time
• Unlike ablative lasers, Fraxel treats only 20–25 percent of your skin in each session leaving
healthy surrounding skin untreated which speeds healing and repair to minimize downtime
• Results are permanent and require little maintenance
Duration of Benefits:• The Fraxel® Laser is applied to your skin in a series of four to five treatment sessions, spaced approximately two to six weeks apart from one another, depending on the problem treated and your skin type• Because collagen production is stimulated during each treatment, patients will experience ongoing improvement lasting well beyound the final treatment • After you have completed the recommended series of treatments, patients will only need to follow up once to twice every two or three years to maintain the beautiful results! Duration of Treatment: 60–90 MinutesFollowing application of a topical anesthetic (45–60 minuts) each treatment takes approximately 15–20 minutes depending on the size of treatment area Treatment Protocol:• Esthetic cleanse of face and neck • Application of topical anesthetic• Customized spa treatment ritual during 30 minute wait time• Laser procedure (15–20 minutes)• Icing (optional five minutes)• Application of moisturizer & sunblock Candidates:Ideal candidates include those with age spots, brown spots, melasma (mask of pregnancy), acne scars, surgical scars, poor skin texture and tone, large pores and wrinkles around the eyes Contraindications:• This procedure should not be administered to pregnant or breastfeeding (lactating) women• If you have an active skin infection or eruption like Rosacea, you are not a candidate at this time What to Expect:• When the laser shines on the skin, patients will experience some discomfort–not unlike a rubber band snapping against the skin• Immediately post treatment, your skin will feel like it’s sunburned. This sensation will usually diminish within one to two hours• New skin will start to form within 24 hours after treatment, but it will remain covered by old skin from four to fourteen days. During this time, natural skin shedding will reveal the repaired epidermal tissue and new skin• You should see some improvement in skin texture shortly after the first treatment Fine lines and deeper lines will also improve but that will take more time• Over the next three to six months, the fibroblasts in the dermis layer of the skin will begin to build new collagen Downtime/Recovery:• Some patients are able to return to routine activities, including work and social obligations, the same day of treatment and others are red and swollen• Redness and swelling is normal following treatment. Healing time varies from person to person• Swelling generally resolves in one to three days • On occasion, there are small areas where the skin may actually peel. This is normal and the skin will heal without issue or scarring • A small degree of redness may last a month or two longer in some cases• Abnormal color and uneven skin tones will improve with each treatment Pre-treatment Guidelines:
Fraxel® Laser Treatment
Six to twelve months before treatment:
• Advise if you have ever had a cold sore (arrange for pre-treatment with Valtrex®) Four weeks before treatment:
• If you have the tendency to hyperpigment we recommend a bleaching regimen at this point • Stay hydrated! Drinking plenty of water before, during and after your treatment will assist with healing Two weeks before treatment:
• Cease use of all retinols, Retin-A, Tazorac®, Differin®, “anti-aging” products containing glycolic, alpha-hydroxy and beta-hydroxy acids • Avoid all sun exposure and/or tanning beds • Cease waxing and other hair-removal procedures • Avoid use of systemic steroids (prednisone, dexamethasone) throughout course of Fraxel® treatment One week before treatment:
• Cease the use of all exfoliants, including microdermabrasion treatments• Order RX for Valtrex® pre-treatment One day before treatment:
• All patients should start pre-treatment with Valtrex®. Take one pill two times per day
Post-treatment Recommendations/Prescriptive Care: Fraxel® Laser Treatment• Apply post-operative ice packs five to ten minutes at a time, every one to two hours post treatment to help reduce swelling and redness• Over the counter medication such as Benadryl® (25 mg.) may also decrease some of the swelling and itching and Tylenol® may be used for discomfort, if necessary • Hydrate: Remember to drink plenty of water post procedure as it assists the healing process• Do NOT pick at healing areas to prevent scarring • You may apply makeup immediately after treatment to help mask temporary redness and/or swelling • Avoid direct sunlight and sun exposure for at least three months after treatment Daily Skincare Routine:
• When washing your face, use a gentle, non soap cleanser (such as Cetaphil®).
You can wash as early as the evening following your treatment
• Most skin care products can be used three weeks after treatment; however, avoid use of
retinoids and topical corticosteroids for two weeks following treatment and avoid systemic
steroids throughout the course of your Fraxel® treatments
• Apply a neutral barrier cream without alpha hydroxy acids (such as Aquaphor®) as often as needed to help treat itching, dryness, flaking and dry crusting. These symptoms will gradually disappear• Use a sunscreen with an SPF of 25 or higher daily Product Recommendations:• Aquaphor® will keep sensitive spots lubricated; an over the counter antibiotic ointment may also be used• Ask your esthetician for specific product recommendations (such as Epidermal Repair Cream) Follow Up Visit:
• A follow up visit will be scheduled approximately five to seven days post-treatment
Call the office immediately if you have any unexpected problems after the procedure
Date: _____________________________________________________________________________
Technician Name: _________________________________________________________________
Notes: ____________________________________________________________________________
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Source: http://www.jspamedspa.com/content/facts/JSPA_Factsheet_Fraxel_web.pdf


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IJBPAS, May, 2013, 2(5): 1151-1159 ISSN: 2277–4998 A REVIEW ON ESOPHAGITIS INDUCED MODEL ARYA E*AND JOSHI H Faculty of Pharmacy, Naraina Vidya Peeth Group of Institutions, Panki, Kanpur *Corresponding Author: E Mail: [email protected]; Ph.: 08574688230 ABSTRACT The term esophagitis is any inflammation of the squamous esophageal epithelium, irritation, or swelling in

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