Happy cat – veterinary data sheet

Happy Cat™
Veterinary Indications
Veterinary Data Sheet
It is always important to identify the underlying reason for the expe-rience of stress, so as to discover a positive solution for it where Happy Cat™ is part of an integrated approach to the treatment and prevention of feline stress-related behaviours and diseases, and to Mood disorders
Ingredients
Happy Cat™ contains 70g Radix Valeriana officinalis – Valerian rhi- Behaviour disorders
 Hyperactivity, restlessness  Inter-cat aggression Phytochemistry
Research on the single ingredient of Happy Cat™ has tended to Psychosomatic disorders
focus on its relaxant or sedative action. Phytochemical constituents currently regarded as most important in clinical action are:  Monoterpenes (borneol) and sesquiterpenes (valerenic acid,  Indigestion – anorexia, vomiting, diarrhoea, colitis, constipation valeranone, kessil glycol) contained in the volatile oil fraction.  Valepotriates including dihydrovaltrates, valtrates and Convalescence
 Baldrinals (valepotriate degradation products), including ho-  Cage rest after post-trauma, post-surgery  Lignans, including 1-hydroxypinoresinol. Musculoskeletal
 Amino acids, including γ-aminobutyric acid (GABA), glutamine, Stressful Events
Pharmacology
Research indicates that the active ingredient in Happy Cat™ pro- motes an increase in the activity of GABA (γ-aminobutyric acid). GABA is the primary inhibitory neurotransmitter in the CNS. Happy Cat™ may therefore enhance the biochemical and behavioural ef- Environmental enrichment
Dosage Guidelines
 0.02-0.30g/kg/day (divided BID or TID)  up to 1 pinch /kg/day (divided BID or TID)  1 g = 3 pinches dried valerian root on average Higher dosing appropriate for severe, acute conditions. Lower dose appropriate to prevent symptoms or as environmental enrichment. [*based on animal studies, human data and clinical veterinary ex-perience.] Herb Quality
Happy Cat™ contains medical grade herb material, and is certified free of pesticides, heavy metals, aflatoxins. Fig 1 – Possible sites of action of Happy Cat™. Safety and Toxicity
Valerian officinalis root has been show to: 1. Itself contain GABA, 2. Happy Cat™ contains one ingredient only – Valeriana officinalis. Activate glutamate decarboxylase (GAD) – an enzyme involved in Valerian may generally be considered a safe herb for felines. How- GABA synthesis in presynaptic nerves, 3. Inhibit GABA reuptake in ever, herbs with anxiolytic and sedative actions should ideally be glial cells and neurons, 4. Inhit GABA transaminase – an enzyme used for a limited duration. Underlying reasons for disease should involved in GABA catabolism, 5. Bind to GABAA receptors. These always be sought and changes made wherever and whenever pos- effects lead to a potentiation of the action of GABA and an increased  Contraindications - None known.
Clinical Actions
 Herb-drug interactions - No significant herb/drug interactions
with Valeriana officinalis have been reported in humans or ani- Happy Cat™ offers the following benefits to felines: mals. Caution is, nevertheless, advised when using in combina- tion with barbiturates, anaesthetics, and other central nervous  Feline Attractant – naturally attractive to cats allowing easy
 Pregnancy - No evidence of increased foetal damage in animal
 Anxiolytic - helps to alleviate anxiety, nervous tension. Facili-
 Lactation – Valeriana officinalis is regarded as safe in breast-
 Sedative – assists in reducing hyper-excitability and hyper-
feeding in humans. The safety of Valerian during lactation in other animals has not been established, therefore administer  Muscle Relaxant - helps relieve skeletal and smooth muscle
 Overdose - Doses up to 20 times the recommended therapeutic
 Anticonvulsive – helps calm seizure activity. Promotes balance.
dose have caused only mild symptoms. Very large doses may  Hypotensive - supports a lowering of blood pressure and a re-
cause bradycardia and arrhythmias, and decrease intestinal mo- tility. The recommended first aid is gastric lavage, charcoal  Analgesic – assists in relieving pain associated with physical

Source: http://www.happinessis.co.za/PDFdocs/Happy%20Cat%20Veterinary%20Data%20Sheet.pdf