NAME OF P RODUCT: Dip h e n h yd ra m in e HCl
NSF Reference Standards are for test and assay use only and are not intended for
human or animal consumption. This document communicates information relating to
test and assay use only and may not be applicable for any unauthorized use.
SECTION 1: PRODUCT AND COMPANY IDENTIFICATION
2-(Diphenylmethoxy)-N,N-dimethylethylamine hydrochloride
Contact Information: NSF International 789 N. Dixboro Road Ann Arbor, MI 48113-0140, USA Toll Free (USA): 800-NSF-MARK (800-673-6275) Telephone: (+1) 734-769-8010 Fax: (+1) 734-769-0109
SECTION 2: COMPOSITION/INFORMATION ON INGREDIENTS
% by Weight: 100% Toxicological Data on Ingredients: Acute ORAL (LD50): 500 mg/kg [Rat]
SECTION 3: HAZARDS IDENTIFICATION Potential Acute Health Effects: Extremely hazardous in case of eye contact (irritant). Very hazardous in case of ingestion and inhalation. Hazardous in case of skin contact (irritant). Inflammation of the eye is characterized by redness, watering and itching. Potential Chronic Health Effects:
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
The substance is toxic to lungs, mucous membranes. Repeated or prolonged exposure to the substance can product target organ damage. CARCINOGENIC EFFECTS: Classified 2 (Reasonably anticipated) by NTP. MUTAGENIC EFFECTS: Not Available. TERATOGENIC EFFECTS: Not Available. DEVELOPMENTAL TOXICITY: Not Available.
SECTION 4: FIRST AID MEASURES Eye Contact: Check for and remove contact lenses. Flush eyes with plenty of water for at least 15 minutes. Seek medical attention. Cold water may be used do not use eye ointment. Skin Contact: In case of contact, immediately wash skin with non-abrasive soap and plenty of water. Cover skin with an emollient. Seek medical attention if irritation persists. Cold water may be used. Wash contaminated clothing before reusing. Serious Skin Contact: Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention. Inhalation: If inhaled, remove to fresh air. Seek immediate medical attention. Serious Inhalation: Not Available Ingestion: Do not induce vomiting. Loosen tight clothing. If the victim is not breathing perform mouth-to-mouth resuscitation. Seek immediate medical attention. Serious Ingestion: Not Available. SECTION 5: FIRE-FIGHTING MEASURES
Flammability of the Product: May be combustible at high temperature. Auto-Ignition Temperature: Not Available. Flammable Limits: Not Available. Flash Points: Not Available. Products of Combustion: These products are carbon oxides (CO, CO2), and nitrogen oxides (NO, NO2…), and hydrogen chloride. Fire Hazards in Presence of Various Substances: Not Available. Explosion Hazards in Presence of Various Substances: Risks of explosion of the product in presence of mechanical impact: Not Available. Risks of explosion of the product in presence of static discharge: Not Available. Special Remarks on Fire Hazards: Not Available.
NSF Reference Standards
789 N. Dixboro Road, Ann Arbor, Michigan 48105-9723 USA
+1.734.214.6234 tel • +1.734.827.7792 fax •
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
Special Remarks on Explosion Hazards: Not Available. Fire Fighting Media and Instructions: SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
SECTION 6: ACCIDENTAL RELEASE MEASURES
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface. Dispose of according to local and regional authority requirements. Large Spill: Use appropriate tools to put the material into a suitable waste disposal container. Finish cleaning by spreading water on the contaminated surface. Dispose of according to local and regional authority requirements.
SECTION 7: HANDLING AND STORAGE
Precautions: Provide sufficient air exchange and/or exhaust in work rooms. Avoid dust formation. Keep away from incompatible materials. Wear personal protective equipment. Avoid contact with skin, eyes and clothing. Do not ingest. Do not breathe vapors/dust. Keep away from heat and sources of ignition. Handle in accordance with good industrial hygiene and safety practice. Storage: Keep in original container tightly closed in a dry, cool and well-ventilated place. Protect from light.
SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION
Engineering Controls: If laboratory operations generate dust, fume or mist, use local exhaust ventilation or other appropriate engineering controls to keep exposure to airborne contaminants below the exposure limit. Personal Protection: Splash goggles, lab coat, dust respirator and gloves. Be sure to use an approved/certified respirator or equivalent. Personal Protection in Case of a Large Spill: Splash goggles, full suit, dust respirator, boots and gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
NSF Reference Standards
789 N. Dixboro Road, Ann Arbor, Michigan 48105-9723 USA
+1.734.214.6234 tel • +1.734.827.7792 fax •
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES
Physical state and appearance: Solid. Odor: Not Available. Taste: Not Available. Molecular Weight: 291.82 g/mol Color: White. pH (1% soln/water): Not Available. Boiling Point: Decomposes. Melting Point: 168oC (334.4oF) Critical Temperature: Not Available. Specific Gravity: Density: Not Available. Vapor Pressure: Not Applicable. Vapor Density: Not Available. Volatility: Not Available. Odor Threshold: Not Available. Water/Oil Dist. Coeff: Not Available. Ionicity (in Water): Not Available. Dispersion Properties: See solubility in water. Solubility: Easily soluble in cold and hot water.
SECTION 10: STABILITY AND REACTIVITY
Stability: The product is stable. Instability Temperature: Not Available. Conditions of Instability: Not Available. Corrosivity: Non-corrosive in presence of glass. Special Remarks on Reactivity: Not Available. Special Remarks on Corrosivity: Not Available. Polymerization: Will not occur.
SECTION 11: TOXICOLOGICAL INFORMATION Routes of Entry: Eye contact, Inhalation and ingestion. Toxicity to Animals: Acute ORAL (LD50): 500 mg/kg [Rat] Chronic effects on humans: Carcinogenic Effects classified 2 (Reasonably anticipated) by NTP. The substance is toxic to lungs and mucous membranes. NSF Reference Standards
789 N. Dixboro Road, Ann Arbor, Michigan 48105-9723 USA
+1.734.214.6234 tel • +1.734.827.7792 fax •
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
Other Toxic Effects on Humans: Vey hazardous in case of ingestion and inhalation. Hazardous in case of skin contact (irritant). Special Remarks on Toxicity to Animals: Not Available. Special Remarks on Chronic Effects on Humans: Embryotoxic and/or fetotoxic in animal. Special Remarks on other Toxic Effects on Humans: Not Available.
SECTION 12: ECOLOGICAL INFORMATION Ecotoxicity: Not Available. BOD5 and COD: Not Available. Products of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. Toxicity of the Products of Biodegradation: The products of degradation are more toxic. Special Remarks on the Products of Biodegradation: Not Available. SECTION 13: DISPOSAL CONSIDERATIONS
Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
SECTION 14: TRANSPORT INFORMATION DOT Classification: Toxic Solid Class 6.1 Identification: UN2811 Toxic Solid, Organic N.O.S. (Diphenhydramine Hydrochloride) Class 6.1 PG III. Special Provisions for Transport: Not Applicable. SECTION 15: REGULATORY INFORMATION
Federal and State Regulations: TSCA 8(b) inventory: No products were found. Other Regulations: OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). Other Classifications: WHMIS (Canada): CLASS D-2A: Material causing other toxic effects (VERY TOXIC). DSCL (EEC): Not Available.
NSF Reference Standards
789 N. Dixboro Road, Ann Arbor, Michigan 48105-9723 USA
+1.734.214.6234 tel • +1.734.827.7792 fax •
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
R25- Toxic if swallowed. R36/37/38-Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes. R45- May cause cancer. R63 - Possible risk of harm to the unborn child. S20 - When using do not eat or drink. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37- Wear suitable protective clothing and gloves. S45- In case of accident or if you feel unwell, seek medical advice immediately. S60- This material and its container must be disposed of as hazardous waste. HMIS (U.S.A.): Health Hazard: 3 Fire Hazard: 1 Reactivity: 0 Personal Protection: E National Fire Protection Association (U.S.A.): Health: 3 Flammability: 1 Reactivity: 0 Specific hazard: Protective Equipment: Gloves, lab coat, splash goggles and dust respirator. Be sure to use an approved/certified respirator or equivalent when ventilation is inadequate.
SECTION 16: OTHER INFORMATION References: Not Available. Other Special Considerations: Not Available.
DIS CLAIMER: The information contained in this Material Safety Data Sheet was developed by NSF International staff from sources considered reliable; however the information has not been independently verified by NSF International staff. Therefore this information is provided without any warranty, express or implied regarding its correctness or accuracy, nor will NSF International assume any liability for any loss or damage arising from the use of this information including without limitation direct or indirect losses or expenses. NSF International Reference Standards are intended for use by persons with appropriate technical skills and training. It is solely the responsibility of the user to determine safe conditions for use of this product and to assume liability for any loss, damage or expense whatsoever arising out of the products improper use.
NSF Reference Standards
789 N. Dixboro Road, Ann Arbor, Michigan 48105-9723 USA
+1.734.214.6234 tel • +1.734.827.7792 fax •
NEW MICROBIOLOGICA, 30 , 346-349, 2007 Pharmacokinetics and pharmacodynamics in HAART and antibiotic therapy Marta Boffito St. Stephen’s Centre, Chelsea and Westminster Hospital, London, UK Therapeutic agents used to inhibit the HIV replication are used in combination. The achievement of effective plas-ma concentrations of the drug in its active form, and sustaining such concentrati
Emilie Incerti Formentini porte seule sur scène, comme unique élément scénographique, la chaise sur laquelle elle est assise et prononce les paroles de cette amie maniaco-dépressive de Guillaume Vincent, que le metteur en scène a récoltées six mois durant au cours de face-à-face récurrents, lors de rendez-vous Gare de l’Est justement. Un travail documentaire pour un objet que
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl
NSF Reference Standards are for test and assay use only and are not intended for
human or animal consumption. This document communicates information relating to
test and assay use only and may not be applicable for any unauthorized use.
SECTION 1: PRODUCT AND COMPANY IDENTIFICATION 
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
The substance is toxic to lungs, mucous membranes. Repeated or prolonged exposure to the substance can product target organ damage. CARCINOGENIC EFFECTS: Classified 2 (Reasonably anticipated) by NTP. MUTAGENIC EFFECTS: Not Available. TERATOGENIC EFFECTS: Not Available. DEVELOPMENTAL TOXICITY: Not Available.
SECTION 4: FIRST AID MEASURES 
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
Special Remarks on Explosion Hazards: Not Available. Fire Fighting Media and Instructions: SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet.
SECTION 6: ACCIDENTAL RELEASE MEASURES 
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES 
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
Other Toxic Effects on Humans: Vey hazardous in case of ingestion and inhalation. Hazardous in case of skin contact (irritant). Special Remarks on Toxicity to Animals: Not Available. Special Remarks on Chronic Effects on Humans: Embryotoxic and/or fetotoxic in animal. Special Remarks on other Toxic Effects on Humans: Not Available.
SECTION 12: ECOLOGICAL INFORMATION 
NAME OF P RODUCT: Dip h e n h yd ra m in e HCl MS DS DATE: 22 Ma y, 2012
R25- Toxic if swallowed. R36/37/38-Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes. R45- May cause cancer. R63 - Possible risk of harm to the unborn child. S20 - When using do not eat or drink. S26- In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37- Wear suitable protective clothing and gloves. S45- In case of accident or if you feel unwell, seek medical advice immediately. S60- This material and its container must be disposed of as hazardous waste. HMIS (U.S.A.): Health Hazard: 3 Fire Hazard: 1 Reactivity: 0 Personal Protection: E National Fire Protection Association (U.S.A.): Health: 3 Flammability: 1 Reactivity: 0 Specific hazard: Protective Equipment: Gloves, lab coat, splash goggles and dust respirator. Be sure to use an approved/certified respirator or equivalent when ventilation is inadequate.
SECTION 16: OTHER INFORMATION