Nicotine Content in Tobacco Products Nicotine content Suggested Rx Cigarettes 1.1mg to 1.8mg per cigarette 21mg patch QD x28 days plus NRT gum or (22mg to 36mg/pack) NRT lozenge (4mg/2mg). Evaluate decrease patch dose monthly (PACT nurses to track?). May add Bupropion if no contraindications. 13.3mg average Patch and Short Acting NRT (4mg/2mg) based on # of cigars per day. May add Bupropion if no contraindications. Mini-cigars (i.e. ‘Swishers or Dark Horse) 3.8mg per mini-cigar = 76mg/pack 42mg to 21mg (depending on # smoked) plus Short Acting NRT (4mg/2mg). May add Bupropion if no contraindications. 5.2mg average per bowl Patch and Short Acting NRT (4mg/2mg) based on # of bowls smoked per day. May add Bupropion if no contraindications. Chewing/dipping can (i.e. Skoal, 88mg per can of dip/chew 42mg Patch and Short Acting NRT Copenhagen) (4mg/2mg). May add Bupropion if no contraindications. Loose leaf pouch (i.e. Redman) 144mg per pouch 42mg Patch and Short Acting NRT (4mg/2mg). May add Bupropion if no contraindications. Hookah (water pipe) One 45-60 minute session = approximately 21mg Patch and Short Acting NRT one pack of cigarettes in nicotine and tar (4mg/2mg). May add Bupropion if no contraindications. Bidi’s (hand rol ed cigarettes imported from One bidi contains 3 to 5 times as much Patch and Short Acting NRT (4mg/2mg) based nicotine as a regular cigarette on # of bidi’s smoked per day. May add Bupropion if no contraindications. Kretek (Clove cigarette) Little research available. Increased risk of Short Acting NRT (4mg/2mg) based on # of acute lung injury, especial y with asthma or Kretek’s per day. May add Bupropion if no respiratory infections. contraindications. References available on request Clinical Pearls
• Optimal length of treatment is not established for NRT
• Evidence for using NRT gum/lozenge for 6 months or greater, results in improved quit rates
• Combination of NRT patches and NRT gum/lozenge or NRT patches and gum/lozenge + Bupropion is most effective
• NRT gum/lozenge absorption is affected by pH: advise against drinking coffee, tea, soda, juice while gum/lozenge is in mouth
• Advise using NRT gum/lozenge to ‘stay ahead of the craving’ by using a piece every hour while awake (or at least for the first 3 hours), especially within the first 7-30 days
• Use of Bupropion for 52 weeks produces about 42% successful quit
• Bupropion can be used with Prozac, Zoloft, Celexa and most al meds for depression
• Bupropion contraindicated if: known seizure disorder (ever); structural brain abnormality; serious closed head injury (unconscious for 30 minutes or greater within past 5 years)
• Initial symptom of nicotine toxicity = NAUSEA
• Electronic cigarettes: not regulated; can contain from 0mg to .2mg to 2mg per e-cigarette; many brands contain nitrosamines (cancer causing agents) despite label saying otherwise; active ingredient of antifreeze added to most brands to produce ‘puff of smoke’
• Two problems: 1.) physical addiction to nicotine (out in 72 hours) and, 2.) psychological/behavioral problem. Treating only physical addiction = high failure rate.
• Strongly advocate use of
VA groups and/or individual therapy Quit lines (1-800-QUITNOW or American Lung Association 1-800-784-8937) Internet resources oror) Family/friend support
Appendix 3 – Turnaround Times REPORTING TIME CATEGORIES FOR TURNAROUND TIME FOR CLINICAL BIOCHEMISTRY This document has gone out to consultation with both the East of England Clinical Biochemistry Professional Development Group and the Royal College of Pathologists Speciality Advisory Committee (SAC) for Clinical Biochemistry. Any laboratory service should be quality driven, inc
CONTRATO DE SUMINISTRO DE BIENES DE CONSUMO, PUBLICIDAD Y PROMOCIÓN CON GARANTÍA DE PREFERENCIA QUE CELEBRAN POR UNA PARTE LA EMPRESA DENOMINADA EMBOTELLADORA ZACATECAS, S. A. DE C.V. REPRESENTADA EN ESTE ACTO POR SU APODERADO LEGAL, EL LIC. VICTOR MANUEL OLIVARES MALDONADO, A QUIEN EN LO SUCESIVO SE LE DENOMINARÁ “LA EMBOTELLADORA” Y POR OTRA PARTE EL INSTITUTO SEGURIDAD