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Faculty-In-charge, Instruction DivisionBirla Institute of Technology and Science, PilaniK.K. Birla Goa Campus, Goa 403726+91-832-2580-313/334 Synthesis, Spectroscopic and Electrochemical studies of gold(II), chromium(IV), and copper(II) compounds with unusual electronic structures. Conformationand dynamics as well as structure-function relationships of cytochromeP450 and Inorganic biochemistry of Haemoglobin.
Indian Association for Cultivation of Science / Jadavpur University,Kolkata, India • Thesis Topic: A Study of the Coordination Compounds of Gold with Some Selected Mixed Hard Soft Donor Systems • Advisor: Prof. Sakti Prosad Ghosh, Ph.D Burdwan University, Burdwan, West Bengal, India, B.Sc. (Chemistry Hons.), K.C. College, 1977 Laboratory of Molecular Carcinogenesis, National Cancer Institute,National Institutes of Health, Bethesda, Maryland , USA Department of Chemistry,Indian Institute of Technology - Madras, Chennai Department of Inorganic Chemistry,Indian Association for the Cultivation of Science, Kolkata, India Department of Chemistry,Birla Institute of Technology & Science, PilaniK.K. Birla Goa Campus, Goa, India Department of Chemistry,Birla Institute of Technology & Science, PilaniK.K. Birla Goa Campus, Goa, India Department of Chemistry,Birla Institute of Technology & Science, PilaniK.K. Birla Goa Campus, Goa, India Department of Chemistry,Birla Institute of Technology & Science, PilaniVidyavihar CampusPilani, Rajasthan, India Instruction DivisionBirla Institute of Technology & Science, PilaniK.K. Birla Goa Campus, Goa, India Instruction & Academic Registration and Counseling DivisionsBirla Institute of Technology & Science, PilaniK.K. Birla Goa Campus, Goa, India Member of the American Chemical Society (ACS) Member of the American Association for the Advancement of Science(AAAS) Member of the International Society of Biological Inorganic Chemistry(SBIC) 1. Ghosh, S., Ray, P.K., Saha S.R., and Koley, A.P.: “Ligational behaviour of a tridentate N-N-S donor ligand towards salts of Co(III), Ni(II), and Cu(II).”Indian J. Chem. 23A: 745, 1984.
2. Koley, A.P., Purohit, S., Ghosh, S., Prasad, L.S., and Manoharan, P.T.: “Studies on gold(II) complexes with hard and soft donorligands. Part I. Complexes with o-aminobenzenethiol.” J.Chem.SocDalton Trans. 2607, 1988 3. Purohit, S., Koley, A.P., Prasad, L.S., Manoharan, P.T., and Ghosh, S.: “Chemistry of molybdenum with hard-soft donor ligands.
II. Molybdenum(VI), -(V), and -(IV) oxo complexes with tridentateSchiff base ligand.” Inorg. Chem. 28: 3735, 1989 4. Purohit, S.,Koley, A.P., and Ghosh, S.: “Chemistry of molybdenum with hard-soft donor ligands. III. Oxomolybdenum(VI) and cis-dioxomolybdenum(VI) mixed ligand complexes.”Polyhedron 9: 881,1990 5. Koley, A.P.:“ Gold(II) complexes with hard-soft donor ligands.
6. Koley, A.P., Purohit, S., Prasad, L.S., Ghosh, S., and Manoharan, P.T.: “Studies on gold(II) complexes with hard and soft donorligands: Part II. Complexes with o-methylthioaniline and 1,2-di(o-aminophenylthio)ethane.” Inorg. Chem. 31: 305, 1992 7. Koley, A.P., Nirmala, R., Prasad, L.S., Ghosh, S., and Manoharan, P.T.: “Studies on gold(II) complexes with hard and soft donorligands: Part III. Complexes with N-(2-pyridylmethyl)-2-mercaptoaniline.”Inorg.Chem. 31: 1764, 1992 8. Koley, A.P., Prasad, L.S., Manoharan, P.T., and Ghosh, S.:“ Studies on gold(II) complexes with hard and soft donor ligands:Part IV. A reactivity study in solution using EPR.” Inorg. Chim.
Acta 194: 219,1992 9. Koley, A.P., Robinson, R.C., Markowitz, A., and Friedman, F.K.:“ Kinetics of CO binding to cytochromes P450 in the endoplasmicreticulum.” Biochemistry 33: 2484, 1994 10. Koley, A.P., Robinson, R.C., Markowitz, A., and Friedman, F.K.: “Interaction of polycyclic aromatic hydrocarbons and flavones withcytochromes P450 in the endoplasmic reticulum: Effect on CObinding kinetics.” Biochemistry 34: 1942, 1995 11. Koley, A.P., Buters, J.T.M., Robinson, R.C., Markowitz, A., and Friedman, F.K.: “CO Binding kinetics of human cytochrome P4503A4: Specific interaction of substrates with kinetically distinguishableconformers.” J. Biol. Chem. 270: 5014, 1995 12. Koley, A.P., Robinson, R.C., and Friedman,F.K.: “Cytochrome P450 conformation and substrate interactions as probed by CObinding kinetics.” Biochimie 78: 706, 1996 13. Koley, A.P., Buters, J.T.M., Robinson, R.C., Markowitz, A., and Friedman, F.K.: “Interaction of polycyclic aromatic hydrocarbonswith human cytochrome P450 1A1: A CO flash photolysis study.”Arch. Biochem. Biophys. 336: 261, 1996 14. Koley, A.P., Buters, J.T.M., Robinson, R.C., Markowitz, A., and Friedman, F.K.:“ Differential mechanisms of cytochrome P450inhibition and activation by alpha-naphthoflavone.” J. Biol. Chem.
272: 3149,1997 15. Sanna, M.T., Razynska, A., Karavitis, M., Koley, A.P., Friedman, F.K., Russu, I. M., Brinigar,W.S., and Fronticelli, C.: “Assembly ofhuman hemoglobin: Studies with Escherichia Coli expressed alphaglobin.” J. Biol. Chem. 272: 3478, 1997 16. Koley, A.P., Robinson, R.C., Markowitz, A., and Friedman, F.K.: “Drug-drug interactions: Effect of quinidine on nifedipine bindingto human cytochrome P450 3A4.” Biochem. Pharmacol. 53: 455,1997 17. Koley, A.P., Dai, R., Robinson, R.C., Markowitz, A., and Friedman, F.K.: “Differential interaction of erythromycin with cytochromesP450 3A1/2 in the endoplasmic reticulum: A CO flash photolysisstudy.” Biochemistry 36: 3237, 1997 18. Cupane, A., Leone, M., Mitlitello, V., Friedman, F.K., Koley, A.P., Vasquez, G.B., Brinigar, W.S.,Karavitis, M. and Fronticelli,C.: “Modification of alpha-chain or beta- chain heme pocket polarityby Val(E11)- Thr substitution has different effects on the steric,dynamic and functional properties of human recombinant deoxyhemoglobinDeoxy derivatives.” J. Biol. Chem. 272: 26271, 1997 19. Smith, S.V., Koley, A.P., Dai, R., Robinson, R.C., Leong, H., Markowitz, A. and Friedman, F.K.: “Conformational Modulationof Human Cytochrome P450 2E1 by Ethanol and Other Substrates:A CO Flash Photolysis Study.” Biochemistry 39: 5731, 2000 20. Kumar, M., Ghosh, S. P., Koley, A.P. and Ghosh, M. C.:“ Reduction of carboxylato-bound chromium(IV) by hydrazine.” J. Chem. Research(s) 448, 2000 21. Kumar, M., Ghosh, S. P., Koley, A.P. and Ghosh, M. C.: “Reduction of carboxylato-bound chromium(IV) with hydroxylamine.” IndianJ. Chem. 40A: 827, 2001 22. Ghosh, S. P., Kumar, M.,Koley, A.P., and Ghosh, M. C.: “First direct detection of chromium(IV) as a long lived intermediate inthe oxidation of alcohol by chromium(VI).” J. Chem. Research(s), 346, 2003 23. Koley, M., Sivasubramanian, S. C., Varghese, B., Manoharan, P.
T., Koley, A.P.: “Synthesis and Characterization of Two StableParamagnetic Octahedral Chromium(IV) Complexes with DianionicTridentate SNO Donor Ligands and of a Chromium(III) Complexwith a ONO Donor Ligand.” Inorg. Chim. Acta 361: 1485, 2008 24. Koley, M., Manoharan, P. T., Koley, A.P.: “Synthesis and characterization of a stable paramagnetic hexacoordinated oxochromium(IV) complexwith dianionic tetradentate Schiff base ligand salen.” Inorg. Chim.
Acta 363: 3798, 2010 25. Manjuri K. Koley, Seshadri C. Sivasubramanian, Sumit Biswas, Periakaruppan T. Manoharan & Aditya P. Koley : “Dioxygenbinding and activation by a highly reactive Cr(II) compound containingS,N-donors derived from oaminothiophenol.” J. Coord. Chem., 65,3329 - 3351 (2012) 26. Manjuri K. Koley, Seshadri C. Sivasubramanian, Babu Varghese, Periakaruppan T. Manoharan & Aditya P. Koley (2012): “Aparamagnetic octahedral trans-dihydroxy chromium(IV) complexwith dianionic tetradentate Schiff base salophen, and crystal structureof its trans-diisothiocyanato analogue.” J. Coord. Chem., 65, 3623- 3640 (2012) 1. Koley, A.P. and Friedman, F.K:“ CO binding kinetics of cytochrome P450 in rat liver microsomes.” Middle Atlantic Regional Meeting/AmericanChemical Society. Washington DC, May 1995.
2. Koley, A.P., Robinson, R.C., Markowitz, A. and Friedman, F.K: “CO binding kinetics as a probe for cytochrome P450 conformationand substrate interactions.” International Conference on ProteinFolding and Design. Bethesda, April 1996.
3. Sanna, M.T., Razynska, A., Karavitis, M., Koley, A.P., Friedman, F.K., Russu, I.M., Brinigar, W.S. and Fronticelli, C.: “Expressionand characterization of human hemoglobin with alpha-globin producedin Escherichia Coli.” Biophysical Society Annual Meeting.
4. Kumar, M., Sivasubramanian, S. C. and Koley, A. P.: “Synthesis and characterisation of some novel stable paramagnetic octahedral chromium(IV) complexes.” Modern Trends in Inorganic ChemistrySymposium, Kolkata, December 2001.
5. Kumar, M., Sivasubramanian, S. C., Koley, A. P.: “Synthesis and characterization of novel paramagnetic chromium compounds.”Symposium on Modern Trends in Inorganic Chemistry (MTIC-X),IIT-Bombay, Mumbai, December 2003.
6. Dhillon, H., Kumar, M., Koley, A. P.: “Spectroscopic studies of some copper(II) compounds.” Symposium on Modern Trends inInorganic Chemistry (MTIC-X), IIT-Bombay, Mumbai, December2003.
7. Deshpande, K., Mishra, Rupesh K., Koley, A. P., and Bhand S.: “A high throughput optical biosensor for analysis of dissolvedHg(II) in water.” Proceedings of the International Congress of EnvironmentalResearch (ICER 08), BITS-Pilani Goa Campus, December 2008.
8. Deshpande, K., Koley, A. P., and Bhand, S.: “Miniaturized bioassay for dissolved mecury analysis.” Symposium on AdvancedBiological Inorganic Chemistry (SABIC),TIFR, Mumbai, 4-7 Nov.
2009.
1. Recent Trends in Inorganic Chemistry Symposium (RTIC-I), Indian Association for the Cultivation of Science (IACS), Calcutta, January1985.
2. Modern Trends in Inorganic Chemistry Symposium (MTIC-II), Indian Institute of Technology, (IIT-Madras), Madras, January 1988.
3. Modern Trends in Inorganic Chemistry Symposium (MTIC-III), Tata Institute of Fundamental Research (TIFR), Bombay, November,1989.
4. International Conference on Bioinorganic Chemistry, Indian Institute of Technology, (IIT-Madras), Madras, January 1990.
5. American Society for Biochemistry and Molecular Biology Annual Meeting held in Washington DC, May 21-25, 1994.
6. American Chemical Society National Meeting held in Washington 7. American Society for Biochemistry and Molecular Biology Meeting held in San Francisco, California, May 21-25, 1995.
8. International Conference on Reversible Association in Structural and Molecular Biology held at NIH, Bethesda, Maryland, February13-16, 1996.
9. International Conference on Protein Folding and Design held at NIH, Bethesda, Maryland, April 23-26, 1996.
10. Modern Trends in Inorganic Chemistry Symposium (MTIC-IX), 11. Symposium on Modern Trends in Inorganic Chemistry (MTIC-X), 12. International Workshop on Biosensors for Environmental Analysis, BITS-Pilani Goa Campus, Goa, February 21-23, 2006.
13. The 8th Workshop on Biosensors and Bioanalytical µ-Techniques in Environmental and Clinical Analysis, BITS-Pilani Goa Campus,Goa, October 3-6, 2007.
14. International Congress of Environmental Research (ICER 08),BITS- 15. Symposium on Advanced Biological Inorganic Chemistry (SABIC),TIFR,

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