6th for 630 “biological function of organometallic compounds” and

Joint workshop of the FOR630 “Biological function of organometallic compounds” and the IRTG1422 “Metal Sites in Biomolecules: Structures, Goslar, February 9-12, 2010
Tuesday, 9th Feb. 2010

Ca. 15:00
Arrival in Goslar at “Haus Hessenkopf”
15:00-16:00
Coffee and Cake

16:00-16:20
Reception

16:20-17:00
Prof. Dr. Franc Meyer (Göttingen, IRTG)
Introduction of the group members of the IRTG Prof. Dr. Nils Metzler-Nolte (Bochum, FOR)
“Metals in Medicine”
Introduction of the group members of the FOR
18:30-19:30

Wednesday, 10th Feb. 2010

8:00-9:00
Breakfast

9:15-10:30
Session I: Wanning Hu
Kathrin Splith (Neundorf group, Leipzig, FOR)
“Organometallic compounds and cell-penetrating peptides: A combination with promising features “ Magnus Krüger (Gust group, Berlin, FOR)
„A New Method of Determining Fluorine-Containing Drugs in Biological Steffen Romanski (Schmalz group, Köln, FOR)
„Synthesis of bioactive Fe(CO)3-complexes” Coffee Break
11:00-12:15
Session II: Jan Dittrich

11:00-11:25
Johanna Niesel (Schatzschneider group, Bochum, FOR)
„Manganese tricarbonyl complexes as photoactivable CO releasing Christopher AG Söderberg (Al-Karadaghi group, Lund, IRTG)
„Assembly and stability of yeast frataxin oligomers” Tobias Beck (G.M.Sheldrick group, Göttingen, IRTG)
„Experimental phasing with sticky triangles”
12:30-13:30

13:30-16:00
Free Time (Visiting Goslar, time for taking a walk …)

16:00-17:20
Session III (Boris Burger)

16:00-16:25
Vera Konstanzer (Meyer group, Göttingen, IRTG)
“News from bioinspired copper-sulfur chemistry”
Prof. Dr. Oliver Wenger (Göttingen, prospective IRTG supervisor)
"Long-range electron tunneling and proton-coupled electron transfer"
16:50-17:15
Coffee Break

17:15-18:30
Session IV (Thomas Bayer)
Lotta Glans (Nordlander group, Lund, IRTG)
„Development of new half-sandwich chloroquine analogues with Prof. Dr. Ricardo Mata (Göttingen, prospective IRTG supervisor)
"Computation of enzymatic activation barriers through the use of hybrid
quantum mechanics/molecular mechanics methods".
Dr. Claudia Höbartner (Göttingen, prospective IRTG supervisor)
“Chemically modified RNA and DNA catalysis"

18:30-19:30

19:30 - open end

Thursday, 11th Feb. 2010

8:00-9:00
Breakfast

9:15-10:30
Session V: Hendrik Pfeiffer
Verena Ortmann (Beck-Sickinger group, FOR)
“Carbaborane containing NPY analogs as promising breast cancer Philipp Riesterer (Prokop group, Köln, FOR)
„New gold compounds induce apoptosis in malignant lymphoma and leukemia cells and overcome resistance to vincristine and doxorubicine” Lukasz Raszeja (Metzler-Nolte group, Bochum, FOR)
„Strategies for the cellular uptake of antisense PNA into pancreactic
cancer cells “
Coffee Break

11:00-12:15
Session VI: David Köster

11:00-11:25
Igor Kitanovic (Wölfl group, Heidelberg, FOR)
„Rhenium tricarbonyl complex of 2-azido-N,N-bis((quinolin-2- yl)methyl)ethanamine Bursts Intracellular ROS and Induces Apoptosis in Different Cells Lines” Riccardo Rubbiani (Ott group, Braunschweig, FOR)
“The Glutathione/Thioredoxin Reductase System as Molecular Target for Antiproliferative Gold(I) Carbene Complexes” Alexander Wilbuer (Meggers group, Marburg, FOR)
„Discovery of an Iridium Compound as a Highly Selective Flt4 Kinase
12:30-13:30

14:30-17:00
Tour around the mines of “Rammelsberg”
17:30-18:30
Poster session and beverages

18:30-19:30
Workshop dinner

Friday, 12th Feb. 2010

8:00-9:00
Breakfast

9:40-10:30
Session VII: Tomislav Argirevic
Malte Kokoschka (W.S. Sheldrick group, Bochum, FOR)
„DNA-Intercalation of Iridium(III)-based Bisintercalators Christina Hain (Diederichsen group, Göttingen, IRTG)
„ Histidine analog amino acids providing metal-binding sites derived from bioinorganic model systems” Coffee Break

11:00-11:50
Session VIII: Anja Pomowski
Simone Wöckel (Meyer group, Göttingen, IRTG)
„Synthetic Models for Metallo- -lactamases “
Peer Lukat (Einsle group, Freiburg, IRTG)
„Structure of the Fe(II)/α-ketoglutarate dependent dioxygenase PlaO1” 12:30-13:30
Departure

Source: http://www.biometals.eu/cms/fileadmin/template/Program_IRTG_workshop_2010.pdf