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Microsoft word - atsdr mrls - february 2013.docx

Agency for Toxic Substances and Disease Registry
MINIMAL RISK LEVELS (MRLs)
February 2013
Uncertainty
Name Route tion MRL Factors Endpoint Status Date Number
______________________________________________________________________________________________________________
ACENAPHTHENE Oral Int. 0.6 mg/kg/day 300 Hepatic Final 08/95 83-32-9
ACETONE Inh. Acute 26 ppm 9 Neurol. Final 05/94 67-64-1
Int. 13 ppm 100 Neurol.
Chr. 13 ppm 100 Neurol.
Oral Int. 2 mg/kg/day 100 Hemato.
ACROLEIN Inh. Acute 0.003 ppm 100 Resp. Final 08/07 107-02-8
Int. 0.00004 ppm 300 Resp.
Oral Int. 0.004 mg/kg/day 100 Gastro.
ACRYLAMIDE Oral Acute 0.01 mg/kg/day 30 Repro. Final 12/12 79-06-1
Int. 0.001 mg/kg/day 30 Neurol.
Chr. 0.001 mg/kg/day 30 Neurol.
ACRYLONITRILE Inh. Acute 0.1 ppm 10 Neurol. Final 12/90 107-13-1
Oral Acute 0.1 mg/kg/day 100 Develop.
Int. 0.01 mg/kg/day 1000 Repro.
Chr. 0.04 mg/kg/day 100 Hemato.
ALDRIN Oral Acute 0.002 mg/kg/day 1000 Develop. Final 09/02 309-00-2
Chr. 0.00003 mg/kg/day 1000 Hepatic
ALUMINUM Oral Int. 1.0 mg/kg/day 30 Neurol. Final 09/08 7429-90-5
Chr. 1.0 mg/kg/day 90 Neurol.
AMERICIUM Rad. Acute 4 mSv 3 Develop. Final 10/04 7440-35-9
Chr. 1 mSv/yr 3 Other
AMMONIA Inh. Acute 1.7 ppm 30 Resp. Final 10/04 7664-41-7
Chr. 0.1 ppm 30 Resp.
ANTHRACENE Oral Int. 10 mg/kg/day 100 Hepatic Final 08/95 120-12-7

Oral Acute 0.005 mg/kg/day 10 Gastro. Final 08/07 7440-38-2
Chr. 0.0003 mg/kg/day 3 Dermal
ATRAZINE Oral Acute

0.01 mg/kg/day
100 Body Wt. Final 09/03 1912-24-9
Int. 0.003 mg/kg/day 300 Repro.

BARIUM, SOLUBLE SALTS
0.2 mg/kg/day
100 Renal
7440-39-3
0.2 mg/kg/day
100 Renal
Inh. Acute
0.009 ppm
300 Immuno. Final 08/07 71-43-2
0.006 ppm
300 Immuno.
0.003 ppm
10 Immuno.
0.0005 mg/kg/day
30 Immuno.
BERYLLIUM
0.002 mg/kg/day
300 Gastro. Final
7440-41-7
BIS(2-CHLOROETHYL) ETHER
1000 Body Wt. Final
111-44-4
BIS(CHLOROMETHYL) ETHER
0.0003 ppm
100 Resp.
542-88-1
Inh. Acute
0.3 mg/m3
7440-42-8
Oral Acute
0.2 mg/kg/day
100 Develop.
0.2 mg/kg/day
66 Develop.
BROMODICHLOROMETHANE
Oral Acute
0.04 mg/kg/day
1000 Hepatic Final
0.02 mg/kg/day
1000 Renal
BROMOFORM
Oral Acute
0.7 mg/kg/day
100 Hepatic Final
0.2 mg/kg/day
300 Hepatic
0.02 mg/kg/day
3000 Hepatic
BROMOMETHANE
Inh. Acute
100 Neurol. Final
100 Neurol.
0.005 ppm
100 Neurol.
0.003 mg/kg/day
100 Gastro.
2-BUTOXYETHANOL
Inh. Acute
Hemato. Final
111-76-2
(ETHYLENE GLYCOL MONOBUTYL ETHER)
9 Hemato.
3 Hemato.
Oral Acute
0.4 mg/kg/day
90 Hemato.
0.07 mg/kg/day
1000 Hepatic
Inh. Acute
0.00003 mg/m3
300 Resp.
7440-43-9
0.00001 mg/m3
Oral Int. 0.0005 mg/kg/day 100 Musculo.
Chr. 0.0001 mg/kg/day 3 Renal
CARBON DISULFIDE Inh. Chr. 0.3 ppm 30 Neurol. Final 08/96 75-15-0
Oral Acute 0.01 mg/kg/day 300 Hepatic
CARBON TETRACHLORIDE Inh. Int. 0.03 ppm 30 Hepatic Final 09/05 56-23-5
Chr. 0.03 ppm 30 Hepatic
Oral Acute 0.02 mg/kg/day 300 Hepatic
Int. 0.007 mg/kg/day 100 Hepatic
CESIUM Rad. Acute 4 mSv 3 Develop. Final 10/04 7440-46-2
Chr. 1 mSv/yr 3 Other
CHLORDANE Inh. Int. 0.0002 mg/m3 100 Hepatic Final 05/94 57-74-9
Chr. 0.00002 mg/m3 1000 Hepatic
Oral Acute 0.001 mg/kg/day 1000 Develop.
Int. 0.0006 mg/kg/day 100 Hepatic
Chr. 0.0006 mg/kg/day 100 Hepatic
CHLORDECONE Oral Acute 0.01 mg/kg/day 100 Neurol. Final 08/95 143-50-0
Int.

0.0005 mg/kg/day
100 Renal
0.0005 mg/kg/day
100 Renal

CHLORFENVINPHOS Oral Acute 0.002 mg/kg/day 1000 Neurol. Final 09/97 470-90-6
Int. 0.002 mg/kg/day 1000 Immuno.
Chr.

0.0007 mg/kg/day
1000 Neurol.
CHLORINE
Inh. Acute
Final 11/10 7782-50-5
0.002 ppm
0.00005 ppm
CHLORINE DIOXIDE
0.001 ppm
300 Resp.
10/04 10049-04-4
CHLORITE
0.1 mg/kg/day
30 Neurol. Final
7758-19-2
CHLOROBENZENE
0.4 mg/kg/day
100 Hepatic Final
108-90-7
CHLORODIBROMOMETHANE
Oral Acute
0.1 mg/kg/day
300 Hepatic Final
124-48-1
0.09 mg/kg/day
300 Hepatic
CHLOROETHANE
Inh. Acute
100 Develop. Final
CHLOROFORM
Inh. Acute 0.1 ppm 30 Hepatic Final 09/97 67-66-3
Int. 0.05 ppm 300 Hepatic
Chr. 0.02 ppm 100 Hepatic
Oral Acute 0.3 mg/kg/day 100 Hepatic
Int. 0.1 mg/kg/day 100 Hepatic
Chr. 0.01 mg/kg/day 1000 Hepatic
CHLOROMETHANE Inh. Acute 0.5 ppm 100 Neurol. Final 12/98 74-87-3
Int. 0.2 ppm 300 Hepatic
Chr. 0.05 ppm 1000 Neurol.
4-CHLOROPHENOL Oral Acute 0.01 mg/kg/day 100 Hepatic Final 07/99 106-48-9
CHLORPYRIFOS Oral Acute 0.003 mg/kg/day 10 Neurol. Final 09/97 2921-88-2
Int. 0.003 mg/kg/day 10 Neurol.
Chr. 0.001 mg/kg/day 100 Neurol.
CHROMIUM(III) SOLUBLE PARTICULATES Inh. Int. 0.0001 mg/m3 300 Resp. Final 09/12 16065-83-1
CHROMIUM(III) INSOL. PARTICULATES Inh. Int. 0.005 mg/m3 90 Resp. Final 09/12 16065-83-1
CHROMIUM(VI) Oral Int. 0.005 mg/kg/day 100 Hemato. Final 09/12 18540-29-9
Chr. 0.0009 mg/kg/day 100 Gastro.
CHROMIUM(VI), AEROSOL MISTS Inh.

0.000005 mg/m3
100 Resp.
09/12 18540-29-9
0.000005 mg/m3
100 Resp.
CHROMIUM(VI), PARTICULATES
0.0003 mg/m3
09/12 18540-29-9
0.0001 mg/m3
7440-48-4
0.01 mg/kg/day
100 Hemato.
Rad. Acute
3 Develop.
Oral Acute
0.01 mg/kg/day
3 Gastro. Final
7440-50-8
0.01 mg/kg/day
3 Gastro.
0.1 mg/kg/day
100 Resp.
1319-77-3
0.1 mg/kg/day
1000 Resp.
CYANIDE, SODIUM
0.05 mg/kg/day
100 Repro.
143-33-9
CYHALOTHRIN
Oral Acute
0.01 mg/kg/day
100 Gastro. Final
09/03 68085-85-8
0.01 mg/kg/day
100 Gastro.

CYPERMETHRIN Oral Acute 0.02 mg/kg/day 100 Neurol. Final 09/03 52315-07-8
DDT, P,P'- Oral Acute

0.0005 mg/kg/day
1000 Develop. Final
0.0005 mg/kg/day
100 Hepatic
DIAZINON
0.01 mg/m3
30 Neurol. Final
333-41-5
Oral Acute
0.006 mg/kg/day
100 Neurol.
0.002 mg/kg/day
100 Neurol.
0.0007 mg/kg/day
100 Neurol.
1,2-DIBROMO-3-CHLOROPROPANE
0.0002 ppm
100 Repro.
0.002 mg/kg/day
1000 Repro.
DI-N-BUTYL PHTHALATE
Oral Acute
0.5 mg/kg/day
100 Develop. Final
1,2-DICHLOROBENZENE
Oral Acute
0.7 mg/kg/day
100 Hepatic Final
0.6 mg/kg/day
100 Hepatic
0.3 mg/kg/day
100 Renal
1,3-DICHLOROBENZENE
Oral Acute
0.4 mg/kg/day
100 Hepatic Final
541-73-1
0.02 mg/kg/day
100 Endocr.
1,4-DICHLOROBENZENE
Inh. Acute
10 Ocular
106-46-7
100 Hepatic
0.07 mg/kg/day
100 Hepatic
0.07 mg/kg/day
100 Hepatic
1,2-DICHLOROETHANE
90 Hepatic Final
107-06-2
0.2 mg/kg/day
300 Renal
1,1-DICHLOROETHENE
100 Hepatic Final
0.009 mg/kg/day
1000 Hepatic
1,2-DICHLOROETHENE, CIS-
Oral Acute
1 mg/kg/day
100 Hemato. Final
156-59-2
0.3 mg/kg/day
100 Hemato.
1,2-DICHLOROETHENE, TRANS-
Inh. Acute
1000 Hepatic Final
156-60-5
1000 Hepatic
0.2 mg/kg/day
100 Hepatic
2,4-DICHLOROPHENOL
0.003 mg/kg/day
100 Immuno. Final
120-83-2
1,2-DICHLOROPROPANE
Inh. Acute 0.05 ppm 1000 Resp. Final 12/89 78-87-5
Int. 0.007 ppm 1000 Resp.
Oral Acute 0.1 mg/kg/day 1000 Neurol.
Int. 0.07 mg/kg/day 1000 Hemato.
Chr. 0.09 mg/kg/day 1000 Hepatic
1,3-DICHLOROPROPENE Inh. Int. 0.008 ppm 30 Resp. Final 09/08 542-75-6
Chr. 0.007 ppm 30 Resp.
Oral Int. 0.04 mg/kg/day 100 Gastro.
Chr. 0.03 mg/kg/day 100 Gastro.
2,3-DICHLOROPROPENE Inh. Acute 0.002 ppm 90 Resp. Final 09/08 78-88-6
DICHLORVOS Inh. Acute 0.002 ppm 100 Neurol. Final 09/97 62-73-7
Int. 0.0003 ppm 100 Neurol.
Chr. 0.00006 ppm 100 Neurol.
Oral Acute 0.004 mg/kg/day 1000 Neurol.
Int. 0.003 mg/kg/day 10 Neurol.
Chr. 0.0005 mg/kg/day 100 Neurol.
DIELDRIN Oral Int. 0.0001 mg/kg/day 100 Neurol. Final 09/02 60-57-1
Chr. 0.00005 mg/kg/day 100 Hepatic

DI(2-ETHYLHEXYL)PHTHALATE
0.1 mg/kg/day
100 Repro.
117-81-7
0.06 mg/kg/day
100 Repro.
DIETHYL PHTHALATE
Oral Acute
7 mg/kg/day
300 Repro.
6 mg/kg/day
300 Hepatic
DIISOPROPYL METHYLPHOSPHONATE
0.8 mg/kg/day
100 Hemato. Final
1445-75-6
0.6 mg/kg/day
100 Hemato.
DIMETHYLARSINIC ACID (DMA)
0.02 mg/kg/day
100 Renal
1,1-DIMETHYLHYDRAZINE
0.0002 ppm
300 Hepatic Final
1,2-DIMETHYLHYDRAZINE
0.0008 mg/kg/day
1000 Hepatic Final
540-73-8
1,3-DINITROBENZENE
Oral Acute
0.008 mg/kg/day
100 Repro.
0.0005 mg/kg/day
1000 Hemato.
4,6-DINITRO-O-CRESOL
Oral Acute
0.004 mg/kg/day
100 Neurol. Final
534-52-1
0.004 mg/kg/day
100 Neurol.
2,4-DINITROPHENOL
Oral Acute
0.01 mg/kg/day
100 Body Wt. Final
2,4-DINITROTOLUENE
Oral Acute
0.05 mg/kg/day
100 Neurol. Final
121-14-2
0.002 mg/kg/day
100 Hemato.
2,6-DINITROTOLUENE
0.004 mg/kg/day
1000 Hemato. Final
606-20-2
DI-N-OCTYL PHTHALATE
Oral Acute
3 mg/kg/day
300 Hepatic Final
117-84-0
0.4 mg/kg/day
100 Hepatic
1,4-DIOXANE
Inh. Acute
30 Ocular
123-91-1
300 Resp.
Oral Acute
5 mg/kg/day
100 Develop.
0.5 mg/kg/day
100 Hepatic
0.1 mg/kg/day
100 Hepatic
DISULFOTON
Inh. Acute
0.006 mg/m3
30 Neurol. Final
298-04-4
0.0002 mg/m3
30 Neurol.
Oral Acute
0.001 mg/kg/day
100 Neurol.
0.00009 mg/kg/day
100 Develop.
0.00006 mg/kg/day 1000 Neurol.
ENDOSULFAN
0.005 mg/kg/day
100 Immuno. Final
115-29-7
0.002 mg/kg/day
100 Hepatic
0.002 mg/kg/day
100 Neurol. Final
0.0003 mg/kg/day
100 Neurol.
Oral Acute
0.002 mg/kg/day
30 Neurol. Final
563-12-2
0.002 mg/kg/day
30 Neurol.
0.0004 mg/kg/day
150 Neurol.
ETHYLBENZENE
Inh. Acute
30 Neurol. Final
100-41-4
30 Neurol.
300 Renal
0.4 mg/kg/day
30 Hepatic

ETHYLENE GLYCOL Inh. Acute 2 mg/m3 10 Resp. Final 11/10 107-21-1
Oral Acute 0.8 mg/kg/day 100 Develop.
Int. 0.8 mg/kg/day 100 Develop.
ETHYLENE OXIDE Inh. Int. 0.09 ppm 100 Renal Final 12/90 75-21-8

FLUORANTHENE
Oral Int. 0.4 mg/kg/day 300 Hepatic Final 08/95 206-44-0

FLUORENE Oral Int. 0.4 mg/kg/day 300 Hepatic Final 08/95 86-73-7
FLUORIDE, SODIUM Oral Chr.

0.05 mg/kg/day
3 Musculo. Final 09/03 7681-49-4
FLUORINE
Inh. Acute
Final 09/03 7782-41-4

FORMALDEHYDE Inh. Acute

Final 07/99 50-00-0
0.008 ppm
0.3 mg/kg/day
100 Gastro.
0.2 mg/kg/day
100 Gastro.
FUEL OIL NO.2
Inh. Acute
0.02 mg/m3
1000 Neurol. Final
06/95 68476-30-2
GUTHION (AZINPHOS-METHYL)
Inh. Acute
0.02 mg/m3
30 Neurol. Final
0.01 mg/m3
30 Neurol.
0.01 mg/m3
30 Neurol.
Oral Acute
0.01 mg/kg/day
100 Neurol.
0.003 mg/kg/day
100 Neurol.
0.003 mg/kg/day
100 Neurol.
HEPTACHLOR
Oral Acute
0.0006 mg/kg/day
3000 Repro.
0.0001 mg/kg/day
300 Immuno.
HEXACHLOROBENZENE
Oral Acute
0.008 mg/kg/day
300 Develop. Final
118-74-1
0.0001 mg/kg/day
90 Repro.
0.00005 mg/kg/day
300 Develop.
HEXACHLOROBUTADIENE
0.0002 mg/kg/day
1000 Renal
ALPHA-HEXACHLOROCYCLOHEXANE
0.008 mg/kg/day
100 Hepatic Final
319-84-6
BETA-HEXACHLOROCYCLOHEXANE
Oral Acute
0.05 mg/kg/day
100 Neurol. Final
319-85-7
0.0006 mg/kg/day
300 Hepatic
GAMMA-HEXACHLOROCYCLOHEXANE
Oral Acute
0.003 mg/kg/day
300 Develop. Final
0.00001 mg/kg/day 1000 Immuno.
HEXACHLOROCYCLOPENTADIENE
0.0002 ppm
0.1 mg/kg/day
100 Renal
HEXACHLOROETHANE
Inh. Acute 6 ppm 30 Neurol. Final 09/97 67-72-1
Int. 6 ppm 30 Neurol.
Oral Acute 1 mg/kg/day 100 Hepatic
Int. 0.01 mg/kg/day 100 Hepatic
HEXAMETHYLENE DIISOCYANATE Inh. Int. 0.00003 ppm 30 Resp. Final 10/98 822-06-0
Chr. 0.00001 ppm 90 Resp.
N-HEXANE Inh. Chr. 0.6 ppm 100 Neurol. Final 07/99 110-54-3
HMX (CYCLOTETRAMETHYLENE Oral Acute 0.1 mg/kg/day 1000 Neurol. Final 09/97 2691-41-0
TETRANITRAMINE) Int. 0.05 mg/kg/day 1000 Hepatic
HYDRAZINE Inh. Int. 0.004 ppm 300 Hepatic Final 09/97 302-01-2
HYDROGEN FLUORIDE Inh. Acute 0.02 ppm 30 Resp. Final 09/03 7664-39-3
HYDROGEN SULFIDE Inh. Acute 0.07 ppm 27 Resp. Final 07/06 7783-06-4
Int. 0.02 ppm 30 Resp.
IODIDE Oral Acute

0.01 mg/kg/day
1 Endocr. Final
7553-56-2
0.01 mg/kg/day
1 Endocr.
IONIZING RADIATION, N.O.S.
Rad. Acute
3 Neurol. Final 09/99 HZ1800-45-T
ISOPHORONE
3 mg/kg/day
100 Other
0.2 mg/kg/day
1000 Hepatic
300 Hepatic Final
06/95 50815-00-4
JP-5/JP-8
300 Hepatic Final 10/98 HZ0600-26-T
0.3 mg/m3
300 Hepatic Final 06/95 HZ0600-22-T
KEROSENE
0.01 mg/m3
1000 Hepatic Final
8008-20-6
MALATHION
Inh. Acute
0.2 mg/m3
100 Neurol. Final
121-75-5
0.02 mg/m3
1000 Resp.
0.02 mg/kg/day
10 Neurol.
0.02 mg/kg/day
100 Neurol.
MANGANESE, RESPIRABLE
0.3 ug/m3
100 Neurol. Final
7439-96-5
MERCURIC CHLORIDE
Oral Acute
0.007 mg/kg/day
100 Renal
7487-94-7
0.002 mg/kg/day
100 Renal
0.0002 mg/m3
30 Neurol. Final
7439-97-6
METHOXYCHLOR
0.005 mg/kg/day
1000 Repro.

4,4'-METHYLENEBIS(2-CHLOROANILINE) Oral

0.003 mg/kg/day
3000 Hepatic Final
101-14-4
METHYLENE CHLORIDE
Inh. Acute
100 Neurol. Final
90 Hepatic
30 Hepatic
Oral Acute
0.2 mg/kg/day
100 Neurol.
0.06 mg/kg/day
100 Hepatic
4,4'-METHYLENEDIANILINE
Oral Acute
0.2 mg/kg/day
300 Hepatic Final
101-77-9
0.08 mg/kg/day
100 Hepatic
METHYLMERCURY
0.0003 mg/kg/day
4.5 Develop. Final
03/99 22967-92-6
1-METHYLNAPHTHALENE
0.07 mg/kg/day
1000 Resp.
2-METHYLNAPHTHALENE
0.04 mg/kg/day
100 Resp.
METHYL PARATHION
0.0007 mg/kg/day
300 Neurol. Final
298-00-0
0.0003 mg/kg/day
100 Hemato.
METHYL-T-BUTYL ETHER
Inh. Acute
100 Neurol. Final
1634-04-4
100 Neurol.
100 Renal
Oral Acute
0.4 mg/kg/day
100 Neurol.
0.3 mg/kg/day
300 Hepatic
0.0008 mg/kg/day
100 Hepatic Final
2385-85-5
MONOMETHYLARSONIC ACID
0.1 mg/kg/day
100 Gastro. Final
124-58-3
0.01 mg/kg/day
100 Renal
NAPHTHALENE
0.0007 ppm
300 Resp.
Oral Acute
0.6 mg/kg/day
90 Neurol.
0.6 mg/kg/day
90 Neurol.
N-NITROSODI-N-PROPYLAMINE
Oral Acute
0.095 mg/kg/day
100 Hepatic Final
621-64-7
Inh. Int. 0.0002 mg/m3 30 Resp. Final 09/05 7440-02-0
Chr. 0.00009 mg/m3 30 Resp.
2,3,4,7,8-PENTACHLORODIBENZOFURAN Oral Acute 0.001 ug/kg/day 3000 Immuno. Final 05/94 57117-31-4
Int. 0.00003 ug/kg/day 3000 Hepatic
PENTACHLOROPHENOL Oral Acute 0.005 mg/kg/day 1000 Develop. Final 09/01 87-86-5
Int. 0.001 mg/kg/day 1000 Repro.
Chr. 0.001 mg/kg/day 1000 Endocr.
PERCHLORATES Oral Chr. 0.0007 mg/kg/day 10 Endocr. Final 08/08 7778-74-7
PERMETHRIN Oral Acute 0.3 mg/kg/day 100 Neurol. Final 09/03 52645-53-1
Int. 0.2 mg/kg/day 100 Neurol.
PHENOL Oral Acute 1 mg/kg/day 100 Body Wt. Final 09/08 108-95-2
PHOSPHORUS, WHITE Inh. Acute 0.02 mg/m3 30 Resp. Final 09/97 7723-14-0
Oral Int. 0.0002 mg/kg/day 100 Repro.
POLYBROMINATED BIPHENYLS (PBBs) Oral Acute 0.01 mg/kg/day 100 Endocr. Final 10/04 36355-01-8
POLYBROMINATED DIPHENYL ETHERS Inh Int.

0.006 mg/m3
90 Endocr. Final
10/04 32534-81-9
(PBDEs), LOWER BROMINATED
Oral Acute
0.03 mg/kg/day
30 Endocr.
32536-52-0
0.007 mg/kg/day
300 Hepatic
PBDEs, DECABROMINATED
10 mg/kg/day
100 Develop. Final
1163-19-5
POLYCHLORINATED BIPHENYLS (PCBs)
0.03 ug/kg/day
300 Neurol. Final
11/00 11097-69-1
(Aroclor 1254)
0.02 ug/kg/day
300 Immuno.
PROPYLENE GLYCOL
0.009 ppm
1000 Resp.
PROPYLENE GLYCOL DINITRATE
Inh. Acute
0.003 ppm
10 Neurol. Final
6423-43-4
0.00004 ppm
1000 Hemato.
0.00004 ppm
1000 Hemato.
RDX (Cyclonite)
Oral Acute
0.2 mg/kg/day
30 Neurol. Final
121-82-4
0.1 mg/kg/day
30 Neurol.
0.1 mg/kg/day
30 Neurol.
REFRACTORY CERAMIC FIBERS
0.03 fibers/cc
Final 10/04 HZ0900-26-T
SELENIUM
0.005 mg/kg/day
7782-49-2

STRONTIUM Oral Int. 2 mg/kg/day 30 Musculo. Final 10/04 7440-24-6
STYRENE Inh. Acute 5 ppm 10 Neurol. Final 11/10 100-42-5
Chr. 0.2 ppm 30 Neurol.
Oral Acute 0.1 mg/kg/day 1000 Neurol.
SULFUR DIOXIDE Inh. Acute 0.01 ppm 9 Resp. Final 12/98 7446-09-5
SULFUR MUSTARD Inh. Acute 0.0007 mg/m3 30 Ocular Final 09/03 505-60-2
Int. 0.00002 mg/m3 30 Ocular
Oral Acute 0.5 ug/kg/day 1000 Develop.
Int. 0.07 ug/kg/day 300 Gastro.
2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN Oral Acute 0.0002 ug/kg/day 21 Immuno. Final 12/98 1746-01-6
Int. 0.00002 ug/kg/day 30 Lymphor.
Chr. 0.000001 ug/kg/day 90 Develop.
1,1,2,2-TETRACHLOROETHANE Oral Int. 0.5 mg/kg/day 100 Hepatic Final 09/08 79-34-5
TETRACHLOROETHYLENE Inh. Acute 0.2 ppm 10 Neurol. Final 09/97 127-18-4
Chr. 0.04 ppm 100 Neurol.
Oral Acute 0.05 mg/kg/day 100 Develop.
TIN, INORGANIC Oral Int. 0.3 mg/kg/day 100 Hemato. Final 09/05 7440-31-5
TIN, DIBUTYL-, DICHLORIDE Oral Int. 0.005 mg/kg/day 1000 Immuno. Final 09/05 683-18-1
TIN, TRIBUTYL-, OXIDE Oral Int. 0.0003 mg/kg/day 100 Immuno. Final 09/05 56-35-9
Chr. 0.0003 mg/kg/day 100 Immuno.
TITANIUM TETRACHLORIDE Inh. Int. 0.01 mg/m3 90 Resp. Final 09/97 7550-45-0
Chr. 0.0001 mg/m3 90 Resp.
TOLUENE Inh. Acute 1 ppm 10 Neurol. Final 09/00 108-88-3
Chr. 0.08 ppm 100 Neurol.
Oral Acute 0.8 mg/kg/day 300 Neurol.
Int. 0.02 mg/kg/day 300 Neurol.
TOXAPHENE Oral Acute 0.05 mg/kg/day 100 Neurol. Draft 09/10 8001-35-2
Int. 0.002 mg/kg/day 100 Immuno.
TRIBUTYL PHOSPHATE Oral Acute 1.1 mg/kg/day 100 Body Wt. Final 09/12 126-73-8
(TnBP) Int. 0.08 mg/kg/day 100 Renal

Chr. 0.08 mg/kg/day 100 Renal
1,2,4-TRICHLOROBENZENE Oral Int. 0.1 mg/kg/day 100 Hepatic Draft 9/10 120-82-1
Chr. 0.1 mg/kg/day 100 Hepatic
1,1,1-TRICHLOROETHANE Inh. Acute 2 ppm 100 Neurol. Final 07/06 71-55-6
Int. 0.7 ppm 100 Neurol.
Oral Int. 20 mg/kg/day 100 Body Wt.
1,1,2-TRICHLOROETHANE Oral Acute 0.3 mg/kg/day 100 Neurol. Final 12/89 79-00-5
Int. 0.04 mg/kg/day 100 Hepatic
TRICHLOROETHYLENE Inh. Chr. 0.0004 ppm 10 Develop. Addendum 01/13 79-01-6
100 Immuno.
Oral Chr. 0.0005 mg/kg/day 10 Develop.
100 Immuno.
1000 Immuno.
1,2,3-TRICHLOROPROPANE Inh. Acute 0.0003 ppm 100 Resp. Final 09/92 96-18-4
Oral Int. 0.08 mg/kg/day 100 Hepatic
TRICRESYL PHOSPHATE Oral Int. 0.04 mg/kg/day 100 Reprod. Final 09/12 1330-78-5
(TCP) Chr. 0.02 mg/kg/day 100 Reprod.
2,4,6-TRINITROTOLUENE Oral Int.

0.0005 mg/kg/day
1000 Hepatic
Final 06/95
118-96-7
TRIS(2-BUTOXYETHYL) PHOSPHATE
Oral Acute
4.8 mg/kg/day
100 Body Wt. Final 09/12
0.09 mg/kg/day
100 Hepatic
TRIS(2-CHLOROETHYL) PHOSPHATE
0.6 mg/kg/day
100 Neurol.
Final 09/12
115-96-8
0.2 mg/kg/day
100 Renal
TRIS(1,3-DICHLORO-2-PROPYL)
0.05 mg/kg/day
100 Renal
Final 09/12 13674-87-8
PHOSPHATE (TDCP)
0.02 mg/kg/day
100 Renal
URANIUM, SOLUBLE SALTS
0.0001 mg/m3
300 Renal
Draft 05/11
7440-61-1
0.00004 mg/m3
100 Renal
Oral Acute
0.002 mg/kg/day
100 Develop.
0.0002 mg/kg/day
300 Renal
URANIUM, INSOLUBLE COMPOUNDS
0.002 mg/m3
100 Renal
Draft 05/11
7440-61-1
0.0008 mg/m3
1000 Resp.
VANADIUM
Inh. Acute
0.0008 mg/m3
7440-62-2
0.0001 mg/m3
0.01 mg/kg/day
10 Hemato.
VINYL ACETATE
100 Resp.
108-05-4
VINYL CHLORIDE
Inh. Acute
30 Develop. Final
30 Hepatic
0.003 mg/kg/day
30 Hepatic
XYLENES, MIXED
Inh. Acute
30 Neurol. Final
1330-20-7
90 Neurol.
300 Neurol.
Oral Acute
1 mg/kg/day
100 Neurol.
0.4 mg/kg/day
1000 Neurol.
0.2 mg/kg/day
1000 Neurol.
0.3 mg/kg/day
3 Hemato. Final
7440-66-6
0.3 mg/kg/day
3 Hemato.

______________________________________________________________________________________________________________

Total number of MRLs: 399
For Duration, Acute = 1 to 14 days, Intermediate = 15 to 364 days, and Chronic = 1 year or longer.
For general information on ATSDR Minimal Risk Levels, see www.atsdr.cdc.gov/mrls.
For more information on a specific MRL, please refer to our Toxicological Profiles,
particularly Appendix A of Profiles written after 1995.
The Profiles can be found online at www.astdr.cdc.gov or ordered via cdcinfo@cdc.gov or 1-800-CDC-INFO.

Source: http://laperouse.info/wordpress/wp-content/uploads/2010/08/ATSDR-Minimum-Risk-Levels-2013.pdf

Awmf online - leitlinie neurologie_ hirnmetastasen

AWMF online - Leitlinie Neurologie: Hirnmetastasen AWMF online A rbeitsgemeinschaft der W issenschaftlichen M edizinischen F achgesellschaften Leitlinien der Deutschen Gesellschaft für Neurologie AWMF-Leitlinien-Register Nr. 030/043 Entwicklungsstufe: 1 Zitierbare Quelle: Leitlinien für Diagnostik und Therapie in der Neurologie; 3. überarbeitete Auflage 2005, I

roche.it

TREATMENT REVIEW Diagnostic and Therapeutic Utility of B-Type Natriuretic Peptide in Patients With Renal Insufficiency and Decompensated Heart Failure Peter A. McCullough, MD, MPH, FACC, FACP, FCCP FAHA,* Kuncheria Joseph, MD,† Vandana S. Mathur, MD‡*Divisions of Cardiology, Nutrition and Preventive Medicine, William Beaumont Hospital, RoyalOak, MI, †Bon Secours Hospital, Venice, FL,

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