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Happy cat – veterinary data sheet
Veterinary Data Sheet
It is always important to identify the underlying reason for the expe-rience of stress, so as to discover a positive solution for it where
™ is part of an integrated approach to the treatment and
prevention of feline stress-related behaviours and diseases, and to
™ contains 70g Radix Valeriana officinalis –
Hyperactivity, restlessness Inter-cat aggression
Research on the single ingredient of Happy Cat™
has tended to
focus on its relaxant or sedative action. Phytochemical constituents
currently regarded as most important in clinical action are:
Monoterpenes (borneol) and sesquiterpenes (valerenic acid,
Indigestion – anorexia, vomiting, diarrhoea, colitis, constipation
valeranone, kessil glycol) contained in the volatile oil fraction.
Valepotriates including dihydrovaltrates, valtrates and
Baldrinals (valepotriate degradation products), including ho-
Cage rest after post-trauma, post-surgery
Lignans, including 1-hydroxypinoresinol.
Amino acids, including γ-aminobutyric acid (GABA), glutamine,
Research indicates that the active ingredient in Happy Cat
motes an increase in the activity of GABA (γ-aminobutyric acid).
GABA is the primary inhibitory neurotransmitter in the CNS. Happy
™ may therefore enhance the biochemical and behavioural ef-
0.02-0.30g/kg/day (divided BID or TID) up to 1 pinch /kg/day (divided BID or TID) 1 g = 3 pinches dried valerian root on average
Higher dosing appropriate for severe, acute conditions. Lower dose appropriate to prevent symptoms or as environmental enrichment. [*based on animal studies, human data and clinical veterinary ex-perience.]
™ contains medical grade herb material, and is certified free of pesticides, heavy metals, aflatoxins.
Fig 1 – Possible sites of action of Happy Cat
Safety and Toxicity
root has been show to: 1. Itself contain GABA, 2.
™ contains one ingredient only – Valeriana officinalis
Activate glutamate decarboxylase (GAD) – an enzyme involved in
Valerian may generally be considered a safe herb for felines. How-
GABA synthesis in presynaptic nerves, 3. Inhibit GABA reuptake in
ever, herbs with anxiolytic and sedative actions should ideally be
glial cells and neurons, 4. Inhit GABA transaminase – an enzyme
used for a limited duration. Underlying reasons for disease should
involved in GABA catabolism, 5. Bind to GABAA receptors. These
always be sought and changes made wherever and whenever pos-
effects lead to a potentiation of the action of GABA and an increased
- None known.
Herb-drug interactions -
No significant herb/drug interactions
with Valeriana officinalis
have been reported in humans or ani-
™ offers the following benefits to felines:
mals. Caution is, nevertheless, advised when using in combina-
tion with barbiturates, anaesthetics, and other central nervous
– naturally attractive to cats allowing easy
No evidence of increased foetal damage in animal
- helps to alleviate anxiety, nervous tension. Facili-
Lactation – Valeriana officinalis
is regarded as safe in breast-
– assists in reducing hyper-excitability and hyper-
feeding in humans. The safety of Valerian during lactation in
other animals has not been established, therefore administer
- helps relieve skeletal and smooth muscle
Doses up to 20 times the recommended therapeutic
– helps calm seizure activity. Promotes balance.
dose have caused only mild symptoms. Very large doses may
- supports a lowering of blood pressure and a re-
cause bradycardia and arrhythmias, and decrease intestinal mo-
tility. The recommended first aid is gastric lavage, charcoal
– assists in relieving pain associated with physical
How to be a "good" medical student J. Med. Ethics doi:10.1136/jme.2003.003848 Updated information and services can be found at: References This article cites 2 articles, 1 of which can be accessed free at: Rapid responses Email alerting Receive free email alerts when new articles cite this article - sign up in the box at the Topic collections Articles on similar topics
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