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The Natural Athlete
Information to Optimize Your Health & Fitness, Naturally
Glucosamine seems to be more effective than chondroitin, and there’s no reliable evidence that the combination of glucosamine and chondroitin is more effective than glucosamine alone. Stick with single ingredient glucosamine sulfate products.
Several clinical studies lasting up to three years show that glucosamine significantly reduces pain and joint tenderness, and increases joint range of motion and overall mobility. For chronic pain relief, glucosamine is as effective as ibuprofen and piroxicam (Feldene). NSAIDs provide a faster reduction in pain, but glucosamine’s effects last
longer and symptoms do not recur soon after discontinuation, as they do with NSAIDs. Glucosamine also seems to be better tolerated than NSAIDs.
Researchers have speculated for years that glucosamine could modify joint structure and possibly reverse or slow disease progression. In 2001, a new study showed that it might actually have this effect. Researchers measured joint space narrowing in patients taking glucosamine. After three years of treatment patients taking glucosamine did not have further joint space narrowing, indicating that glucosamine may have slowed or stopped disease progression.
There are limited treatment choices for patients with OA (osteoarthritis). Recent developments such as new research on glucosamine are making experts re-evaluate the standard treatment for OA. Some experts now consider glucosamine a first-line treatment for OA. Still many others are skeptical. But the evidence now supports using glucosamine for pain and possibly slowing disease progression.
There’s been a lot of hype surrounding MSM. Lots of patients are interested in trying it because of the fantastic claims made by supplement marketers. MSM stands for methylsulfanylmethane and is a metabolite of DMSO (dimethyl sulfoxide). MSM is promoted as having anti-inflammatory and analgesic effects like DMSO, but without the fishy odor. Studies are equivocal surrounding this supplement.
(also known as Cayenne pepper) is effective for temporary symptom relief of
osteoarthritis and other causes of joint or muscle pain. It is a powerful irritant that when
applied topically can produce the feeling of warmth or burning. The constituent,
capsaicin, depletes and prevents the reaccumulation of substance P in local sensory
nerve terminals when capsicum is repeatedly applied topically. Investigators think
substance P is associated with the process of pain transmission in a variety of diseases –
arthritis, psoriasis, and inflammatory bowel disease. Allow three full days of capsaicin use to achieve the full effect
There is some evidence that increasing DIETARY intake might slow progression of OA. Athletes should boost consumption of vegetables and fruits that provide lots of vitamin C, vitamin E, and beta-carotene. High dietary intake of foods that contain these antioxidants might slow progression of OA.
Carbohydrate supplementation during intense exercise and the immune
response of cyclists. Bacurau RF, Bassit RA, Sawada L, Navarro F, Martins E Jr, Costa Rosa LF.
Clin Nutr. 2002 Oct;21(5):423-9.
OBJECTIVE: To evaluate the effect of carbohydrate supplementation upon some aspects
of the immune function in athletes during intense indoor cycling. METHODS: Twelve
male athletes cycled for 20 min at a velocity corresponding to 90% of that obtained at
the anaerobic threshold and rested for 20 min. This protocol was repeated six times.
The athletes received, during the trial, water ad libitum, or a solution of carbohydrate
(95% glucose polymers and 5% fructose. RESULTS: Exercise induced a reduction in
peripheral blood mononuclear cell proliferation (37%) as well as in the production of
cytokines by cultured cells (interleukin-1 (IL-1), interleukin-2 (IL-2), tumor necrosis
factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma), by 37%, 35%, 26% and
16%, respectively). All of these changes were prevented by the ingestion of a
carbohydrate drink by the athletes. The concentration of plasma glutamine, an
important fuel for immune cells, was decreased in the placebo group but maintained in
the group that received carbohydrate. CONCLUSION: Carbohydrate
supplementation affects positively the immune response of cyclists by
avoiding or minimizing changes in plasma glutamine concentration.
Dr. Jason E. Barker
Integrative Sports Medicine & General Practice
Back In Motion Sports Injuries Clinic 11385 SW Scholls Ferry Road Beaverton, OR 97008 503.524.9040 *This information is provided for general informational purposes only and cannot substitute for
medical advice, diagnosis or treatment provided by a medical professional. It is not a substitute
for a medical evaluation and should not take the place of a proper exam by a physician. Copyright 2006 by Dr. Jason E. Barker
The new england journal of medicine This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author’s clinical recommendations. During a routine visit, a 59-year-old woman, who desc
[Downloaded free from http://www.indianjmedsci.org on Monday, December 22, 2008] literature. Another noteworthy fact is that both 2. Jimenez-Jimenez FJ, Puertas I, de Toledo-of our patients were young females, which Heras M. Drug-induced myoclonus: Frequency, is in contrast to previous literature.[2,3] Even the previous case report of myoclonus with quetiapine has been reported in an e