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More research needed issue 19 - oct 12
The Cochrane Library and other sources regularly
publish new reviews, some of which highlight the
Microfracture as the Primary Treatment for
lack of good quality studies on which to base
Osteochondral Lesions of the Talar Dome.
recommendations. This is a good starting point for
identifying a new area of research. The second step is
Many techniques exist for the treatment of
to find out what else has been published. If you
OCLs of the talar dome. Good to excellent re-
would like a literature search on any of these topics
sults can be consistently reached in greater
please contact the Library Service on ext 3831.
than 80% of patients with arthroscopic de-bridement and microfracture. However, addi-tional prospective trials should be undertaken
A systematic evaluation of content, struc-
to determine differences in outcome between
ture, and efficacy of interventions to im-
techniques, size and location of the OCL, and
prove patients' self-management of cancer
other patient quality factors, such as cost and
This analysis provides researchers and clini-
cians with a detailed overview of the various
structural and content components, as well as
various combinations that were tested in inter-
Intralesional steroid injection for benign
vention studies to improve cancer pain man-
vocal fold disorders: A systematic review
agement. However, because of a variety of
limitations, the most efficacious intervention
VFSI is well-tolerated under local anesthesia
remain to be determined in future studies.
in the office setting. The invasiveness and
morbidity of VFSI are low and the side effects
are self-limited. Meta-analyses demonstrated
significant improvements from both objective
and subjective measurements. Further con-
Systematic Review on Sleep Disorders and
trolled studies with longer follow-up periods
may evaluate the effectiveness of VFSI more
Existing research points to the potentially
harmful effects of sleep disorders on obstetric
outcomes. The limited research in this arena
highlights the need for further studies regard-
ing the nature and strength of this relationship.
Given the multiple dimensions of sleep and
pregnancy, multivariate research approaches
that incorporate biological and psychosocial
Endoscopic treatment with argon plasma co-
agulation appears effective in the short-term
outcome of chronic radiation proctopathy.
There is a moderate level of evidence for the
use of sucralfate enemas. Large, randomized,
placebo-controlled studies evaluating endo-
scopic and medical therapies for chronic radia-
Omega-3 Fatty Acids in the Prevention of
Atrial Fibrillation Recurrences after Cardio-
A Systematic Review of Antibiotic Use and
In the subgroup administered omega-3 fatty
Infect ion in Breast Reconstruction: What is
acids at least 4 weeks prior to cardioversion
and continued thereafter, the recurrence rate
of AF was significantly low. More double-blind,
There is no consensus on the necessary dura-
randomized, placebo-controlled, multicenter
tion for antibiotic prophylaxis following breast
studies with high quality and longer follow-up
reconstruction. We found no benefit in patients
periods are needed to affirm our conclusion.
e antibiotics. Standardized definitions for
antibiotic regimens, unit of analysis reporting,
and a new breast reconstruction surgical site
infection grading system is offered to improve
available clinical data to detect undiag-
domized controlled trials are warranted to best
determine an optimal antibiotic regimen.
There is a proliferation of newly developed risk
scores using similar variables, which some-
times perform poorly upon external validation.
Future research should explore the recalibra-
tion, validation and applicability of existing
scores to other settings, particularly in low/
We found no significant association of meno-
middle income countries, and on the utility of
pause with asthma prevalence or incidence
scores to improve diabetes-related outcomes.
except for women reporting use of MHT. How-
ever, these findings result from a small num-
ber of studies, including only 1 large cohort
with incidence rates for pre- as well as post-
menopause. Further studies are needed ad-
Mindfulness-based stress reduction for low
dressing more closely subgroup analyses and
a possible modification of the association of
This review found inconclusive evidence of ef-
fectiveness of MBSR in improving pain inten-
sity or disability in chronic low back pain pa-
tients. However, there is limited evidence that
MBSR can improve pain acceptance. Further
Effects of physiotherapy interventions on
RCTs with larger sample sizes, adequate con-
balance in multiple sclerosis: A systematic
trol interventions, and longer follow-ups are
needed before firm conclusions can be drawn.
These findings indicate small, but significant,
effects of physiotherapy on balance in people
with multiple sclerosis who have a mild to
moderate level of disability. However, evi-dence for severely disabled people is lacking, and further research is needed. http://www.ncbi.nlm.nih.gov/pubmed/22990349
For more information about this newsletter please contact Laura Sims in the library (ext 6688 or 3831)
C h a p t e r 12 MONOPOLY S o l u t i o n s t o t h e O d d - N u m b e r e d P r o b l e m s 1. a. Substitutes for the U.S. Postal Service include email, fax, and private delivery services, such as FedEx or UPS. Substitutes for Lipitor are other statin drugs, such as Zocor, non-statin drugs that also lower cholesterol, and also exercise. Substitutes for Cox Communications include satell
Methods for the Prevention and Treatment of Bark Beetles Provided as a Public Service by The Tano Road Association A Real Life Bark Beetle Scenario Along Tano Road… . “… … one property owner ignored his dying piñon trees. After threeweeks, the bark beetle eggs hatched, the larvae matured, exited the tree,and spread to his other piñon trees. By summer’s end, he had los