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Anapharm europe bioanalytical methods 2013 april

LIST OF BIOANALYTICAL METHODS
NEWLY DEVELOPED OR RECENTLY UPDATED METHODS
Bioanalytical
Compound
Calibration Range
Bioanalytical matrix
Carbidopa ; Levodopa
LC/MS/MS
2-75 ng/mL ; 10-750 ng/mL
Human EDTA Plasma
Carbidopa ; Levodopa
LC/MS/MS
5-250 ng/mL ; 10-2500 ng/mL
Human EDTA Plasma
Budesonide
LC/MS/MS
5-1000 pg/mL
Human EDTA Plasma
Formoterol
LC/MS/MS
0.4-100 pg/mL
Human EDTA Plasma
0.2-20 ng/mL; 0.2-20 ng/mL; 0.1-10 ng/mL Tiotropium
LC/MS/MS
0.5-100 pg/mL
Human EDTA Plasma
LIST OF BIOANALYTICAL METHODS
Bioanalytical
Compound
Calibration Range
Bioanalytical matrix
Page 1 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Betahistine metabolite (2-pyridylacetic acid) Bicalutamide ((R)-(-)Bicalutamide ; (S)-(+) Bicalutamide (R-(-) Bicalutamide ; (S)-(+) Bicalutamide (R-(-) Bicalutamide ; (S)-(+) Budesonide
LC/MS/MS
5-1000 pg/mL
Human EDTA Plasma
Carbidopa ; Levodopa
LC/MS/MS
2-75 ng/mL ; 10-750 ng/mL
Human EDTA Plasma
Carbidopa ; Levodopa
LC/MS/MS
2-100 ng/mL ; 10-750 ng/mL
Human EDTA Plasma
Page 2 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Carbidopa ; Levodopa
LC/MS/MS
5-250 ng/mL ; 10-2500 ng/mL
Human EDTA Plasma
Carbidopa ; Levodopa
LC/MS/MS
5-300 ng/mL ; 10-2500 ng/mL
Human EDTA Plasma
Chlorpheniramine (S-(+)-clorpheniramine ; 2-2000 ng/mL ; 2-600 ng/mL ; 1-400 ng/mL Deflazacort metabolite (21-OH-Deflazacort) Page 3 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Donepezil ((+)-Donepezil ; (-)-Donepezil) Donepezil ((+)-Donepezil ; (-)-Donepezil) Page 4 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Fluticasone
LC/MS/MS
2-250 pg/mL
Human EDTA Plasma
Fluvastatin ((+)-3R,5S-Fluvastatin ; (-) -3S, 5R- Formoterol
LC/MS/MS
0.4-100 pg/mL
Human EDTA Plasma
Page 5 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Ibuprofen (R-(-)-ibuprofen ; S-(+)-ibuprofen) Ibuprofen (R-(-)-ibuprofen ; S-(+)-ibuprofen) Lercanidipine ((-)-R-Lercanidipine ; (+)-S- Linopristin ; Linopristin Metabolite (RPR Linopristin ; Linopristin Metabolite (RPR Page 6 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Metamizol metabolite (4-methylaminoantipyrine) Metoprolol ((+)-R-Metoprolol ; (-)-S-Metoprolol) Morphine ; Morphine-3-beta-D-glucoronide ; Page 7 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Paliperidone ((-) Paliperidone ; (+) Paliperidone) Pentoxyfiline ; Metabolite I ; Metabolite V Page 8 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Salmeterol
LC/MS/MS
2-250 pg/mL
Human EDTA Plasma
Page 9 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Simvastatin ; b-Hydroxy Acid Simvastatin Simvastatin ; b-Hydroxy Acid Simvastatin ∆9-Tetrahydrocannabinol; 11-Hydroxy-∆9- 0.2-20 ng/mL; 0.2-20 ng/mL; 0.1-10 ng/mL Tiotropium
LC/MS/MS
0.5-100 pg/mL
Human EDTA Plasma
Tolterodine ; 5-hydroxymethyl Tolterodine Tolterodine ; 5-hydroxymethyl Tolterodine Page 10 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com Warfarin (R-(+) Warfarin ; S-(-)-Warfarin) Warfarin (R-(+) Warfarin ; S-(-)-Warfarin) Warfarin (R-(+) Warfarin ; S-(-)-Warfarin) Page 11 of 11
Anapharm Europe S.L.U. Encuny, 22, 2nd Floor 08038 Barcelona, Spain Tel. + 34 93 223 8636 info@anapharmeurope.com www.anapharmeurope.com

Source: http://www.anapharmeurope.com/pdf/Anapharm%20Europe%20Bioanalytical%20methods.pdf

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